Evidence map›Paper›PMID 31433857›Full record

ArticleImmunology2019

Gut eosinophils and their impact on the mucus-resident microbiota.

Gurdeep Singh, Andrew Brass, Christopher G Knight, Sheena M Cruickshank

Open access · hybridAbstract read
In one paragraph

Article in Immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. [Expression of GATA1 in bronchial asthma and its effect on the transcription regulation of theZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Emerging functions of tissue-resident eosinophils.The Journal of experimental medicine · 2023
    Review
  12. Article
  13. Living without eosinophils: evidence from mouse and man.The European respiratory journal · 2023
    Review
  14. Article
  15. Eosinophils and eosinophilic immune dysfunction in health and disease.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
  16. Review
  17. Article
  18. Eosinophils and Bacteria, the Beginning of a Story.International journal of molecular sciences · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Gurdeep SinghFaculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.ORCID 0000-0001-9766-672X
Andrew BrassFaculty of Biology, Medicine and Health, Division of Informatics, Imaging and Data Sciences, The University of Manchester, Manchester, UK.ORCID 0000-0002-0389-7058
Christopher G KnightFaculty of Science and Engineering, School of Natural Sciences, The University of Manchester, Manchester, UK.ORCID 0000-0001-9815-4267
Sheena M CruickshankFaculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.ORCID 0000-0002-3047-5475
Manchester Academic Health Science Centre · GBUniversity of Manchester · GB

Funding

Biotechnology and Biological Sciences Research Council
6 · The paper itself

Abstract

The gut has the largest commensal bacterial population in the body and its composition can be impacted by host factors such as production of immunoglobulin A (IgA). Eosinophils in the gut have been implicated in the production of antibacterial factors and maintenance of IgA-secreting plasma cells. We used an eosinophil-deficient mouse (∆dblGATA-1

Indexed as

AnimalsEosinophilsGastrointestinal MicrobiomeHumansImmunoglobulin AIntestinal MucosaMiceMice, KnockoutPlasma CellsImmunoglobulin Aco-housingdiversitygut barrierlittermate controlplasma cells

Identifiers

PMID31433857
PMCPMC6797872
OpenAlexW2969669413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.