Evidence map›Paper›PMID 31433768›Full record

ArticleJournal of hospital medicine2019

An On-Treatment Analysis of the MARQUIS Study: Interventions to Improve Inpatient Medication Reconciliation.

Amanda S Mixon, Sunil Kripalani, Jason Stein, Tosha B Wetterneck, Peter Kaboli, Stephanie Mueller, Elisabeth Burdick, Nyryan V Nolido, Stephanie Labonville, Jacquelyn A Minahan and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of hospital medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Reducing medication errors for adults in hospital settings.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Closed-Loop Medication Management with an Electronic Health Record System in U.S. and Finnish Hospitals.International journal of environmental research and public health · 2023
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Implementation and sustainability of a medication reconciliation toolkit: A mixed methods evaluation.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2020
    Observational
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Amanda S MixonGRECC, VA Tennessee Valley Healthcare System, Vanderbilt University Medical Center, Nashville, Tennessee.
Sunil KripalaniSection of Hospital Medicine, Van-derbilt University Medical Center, Nashville, Tennessee.
Jason SteinSection of Hospital Medicine, Emory University School of Medicine, Atlanta, Georgia, and 1Unit, Atlanta, Georgia.
Tosha B WetterneckDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Peter KaboliCenter for Access Delivery Research and Evaluation, Iowa City VA Healthcare System, Iowa City, Iowa, and Division of General Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa.
Stephanie MuellerHospital Medicine Unit, Brigham Health, Boston, Massachusetts.
Elisabeth BurdickDivision of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts.
Nyryan V NolidoDivision of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts.
Stephanie LabonvilleDepartment of Pharmacy, Brigham and Women's Hospital, Boston, Massachusetts.
Jacquelyn A MinahanUniversity of Kansas, Lawrence, Kansas.
E John OravHarvard T.H. Chan School of Public Health, Boston, Massachusetts.
Jenna GoldsteinSociety of Hospital Medicine, Philadelphia, Pennsylvania.
Jeffrey L SchnipperHospital Medicine Unit, Brigham Health, Boston, Massachusetts.
Brigham and Women's Hospital · USHarvard University · USEmory University Hospital · USIowa City VA Health Care System · USUniversity of Kansas · USUniversity of Wisconsin–Madison · USVanderbilt University Medical Center · USVA Tennessee Valley Healthcare System · US

Funding

Multi-Center Medication Reconciliation Quality Improvement Study - MARQUISR18HS019598 · AHRQ · SOCIETY OF HOSPITAL MEDICINE · PI SCHNIPPER, JEFFREY LAWRENCE · 2010 to 2012
$1.5M
AHRQ HHS R18 HS019598
6 · The paper itself

Abstract

It is unclear which medication reconciliation interventions are most effective at reducing inpatient medication discrepancies. Five United States hospitals' interdisciplinary quality improvement (QI) teams were virtually mentored by QI-trained physicians. Sites implemented one to seven evidence-based interventions in 791 patients during the 25-month implementation period. Three interventions were associated with significant decreases in potentially harmful discrepancy rates: (1) defining clinical roles and responsibilities, (2) training, and (3) hiring staff to perform discharge medication reconciliation. Two interventions were associated with significant increases in potentially harmful discrepancy rates: training staff to take medication histories and implementing a new electronic health record (EHR). Hospitals should focus first on hiring and training pharmacy staff to assist with medication reconciliation at discharge and delineating roles and responsibilities of clinical staff. We caution hospitals implementing a large vendor EHR, as medication discrepancies may increase. Finally, the effect of medication history training on discrepancies needs further study.

Indexed as

InpatientsCommunicationElectronic Health RecordsHumansInservice TrainingMedication ErrorsMedication ReconciliationPersonnel Staffing and SchedulingPharmacy Service, HospitalProfessional RoleQuality ImprovementUnited States

Identifiers

PMID31433768
PMCPMC6817307
OpenAlexW2963942139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.