Evidence map›Paper›PMID 31433698›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2019

Methamphetamine Use and Cardiovascular Disease.

Christopher G Kevil, Nicholas E Goeders, Matthew D Woolard, Md Shenuarin Bhuiyan, Paari Dominic, Gopi K Kolluru, Connie L Arnold, James G Traylor, A Wayne Orr

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07459244 (Electrocardiogram Findings in Methamphetamine Use Disorder and Methamphetamine-Induced Psychotic Disorder), which is not on this map. Cited by 154 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
154citing papers in PubMed, 4 pooled it
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07459244 recruitingnot on this mapstarted 2025, after this paper: background citation

Electrocardiogram Findings in Methamphetamine Use Disorder and Methamphetamine-Induced Psychotic Disorder: A Prospective Observational Cohort Study

TypeobservationalSponsorElazığ Mental Health and Diseases HospitalRan2025 to 2026Enrolled240ConditionsMethamphetamine Use Disorder, Methamphetamine Induced Psychosis
3 · Its place in the literature

Who cites it

154 citing papers in PubMed, 4 syntheses or guidelines pooled it, 271 citations in OpenAlex.

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  9. Toxidromes.Nature reviews. Disease primers · 2026
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94 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Christopher G KevilFrom the Departments of Pathology and Translational Pathobiology (C.G.K., M.S.B., G.K.K., J.G.T., A.W.O.), LSU Health Sciences Center, Shreveport, LA.
Nicholas E GoedersPharmacology, Toxicology, and Neuroscience (N.E.G.), LSU Health Sciences Center, Shreveport, LA.
Matthew D WoolardMicrobiology and Immunology (M.D.W.), LSU Health Sciences Center, Shreveport, LA.
Md Shenuarin BhuiyanFrom the Departments of Pathology and Translational Pathobiology (C.G.K., M.S.B., G.K.K., J.G.T., A.W.O.), LSU Health Sciences Center, Shreveport, LA.
Paari DominicMedicine (P.D., C.L.A.), LSU Health Sciences Center, Shreveport, LA.
Gopi K KolluruFrom the Departments of Pathology and Translational Pathobiology (C.G.K., M.S.B., G.K.K., J.G.T., A.W.O.), LSU Health Sciences Center, Shreveport, LA.
Connie L ArnoldMedicine (P.D., C.L.A.), LSU Health Sciences Center, Shreveport, LA.
James G TraylorFrom the Departments of Pathology and Translational Pathobiology (C.G.K., M.S.B., G.K.K., J.G.T., A.W.O.), LSU Health Sciences Center, Shreveport, LA.
A Wayne OrrFrom the Departments of Pathology and Translational Pathobiology (C.G.K., M.S.B., G.K.K., J.G.T., A.W.O.), LSU Health Sciences Center, Shreveport, LA.
Louisiana State University Health Sciences Center Shreveport · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI JUDD E SHELLITO · 2012 to 2026
$69.1M
Stress Exacerbates Myocardial Ischemic Injury by Blocking Estrogen's Antidoxidant Protection in the Female HeartP20GM121307 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI Gopi K Kolluru · 2018 to 2026
$23.6M
Nck Adaptor Proteins in Atherogenic Endothelial ActivationR01HL133497 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI ORR, ANTHONY WAYNE · 2016 to 2024
$3.8M
Matrix Signaling in Endothelial Cell DysfunctionR01HL098435 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI ORR, ANTHONY WAYNE · 2010 to 2020
$3.2M
Sigmar1 in lipid metabolismR01HL145753 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI BHUIYAN, MD. SHENUARIN · 2019 to 2023
$2.6M
EphA2 signaling in atherosclerotic fibroproliferative remodelingR01HL141155 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI ORR, ANTHONY WAYNE · 2019 to 2022
$1.8M
Macrophage- associated lipin-1 lipid synthesis regulates foam cell inflammatory responsesR01HL131844 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI WOOLARD, MATTHEW DALE · 2017 to 2020
$1.4M
Sigma-1 receptor and cardioprotectionR00HL122354 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI BHUIYAN, MD. SHENUARIN · 2015 to 2017
$747k
Sigma-1 receptor and cardioprotectionK99HL122354 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI BHUIYAN, MD. SHENUARIN · 2014 to 2015
$263k
NHLBI NIH HHS K99 HL122354NHLBI NIH HHS R00 HL122354NHLBI NIH HHS R01 HL098435NHLBI NIH HHS R01 HL131844NHLBI NIH HHS R01 HL133497NHLBI NIH HHS R01 HL141155NHLBI NIH HHS R01 HL145753NIGMS NIH HHS P20 GM121307NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

While the opioid epidemic has garnered significant attention, the use of methamphetamines is growing worldwide independent of wealth or region. Following overdose and accidents, the leading cause of death in methamphetamine users is cardiovascular disease, because of significant effects of methamphetamine on vasoconstriction, pulmonary hypertension, atherosclerotic plaque formation, cardiac arrhythmias, and cardiomyopathy. In this review, we examine the current literature on methamphetamine-induced changes in cardiovascular health, discuss the potential mechanisms regulating these varied effects, and highlight our deficiencies in understanding how to treat methamphetamine-associated cardiovascular dysfunction.

Indexed as

Arrhythmias, CardiacAtherosclerosisCardiomyopathiesCardiovascular DiseasesHumansHypertension, PulmonaryMethamphetamineVasoconstrictionMethamphetamineatherosclerosiscardiac arrhythmiascardiomyopathymethamphetaminepulmonary hypertensionsubstance-related disordersvasoconstriction

Identifiers

PMID31433698
PMCPMC6709697
OpenAlexW2969628213

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.