Evidence map›Paper›PMID 31433691›Full record

ArticleAmerican journal of physiology. Cell physiology2019

The impact of skeletal muscle contraction on CD146

Svyatoslav Dvoretskiy, Koyal Garg, Michael Munroe, Yair Pincu, Ziad S Mahmassani, Charlotte Coombs, Brent Blackwell, Gabriela Garcia, Garret Waterstradt, Isaac Lee and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. MuSCs and IPCs: roles in skeletal muscle homeostasis, aging and injury.Cellular and molecular life sciences : CMLS · 2024
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Fibroblast Heterogeneity in Healthy and Wounded Skin.Cold Spring Harbor perspectives in biology · 2022
    Article
  9. Optimization of a pericyte therapy to improve muscle recovery after limb immobilization.Journal of applied physiology (Bethesda, Md. : 1985) · 2022
    Article
  10. [The role of CD146 in mesenchymal stem cells].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Svyatoslav DvoretskiyDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Koyal GargBeckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Michael MunroeDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Yair PincuDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Ziad S MahmassaniDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Charlotte CoombsBeckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Brent BlackwellDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Gabriela GarciaDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Garret WaterstradtDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Isaac LeeDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Jenny DrnevichRoy J. Carver Biotechnology Center, High Performance Biological Computing, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Justin S RhodesDepartment of Psychology and Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Marni D BoppartDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois.
University of Illinois Urbana-Champaign · US

Funding

Tissue microenvironment (TIMe) training programT32EB019944 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BHARGAVA, ROHIT, GASKINS, REX · 2016 to 2025
$1.9M
Development of a Cell-Based Therapy to Improve Recovery Following ImmobilizationR01AR072735 · NIAMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, MARNI D. · 2018 to 2022
$1.7M
Origins of exercise-brain interactionsR21NS104293 · NINDS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, MARNI D., RHODES, JUSTIN S · 2018 to 2019
$403k
NIAMS NIH HHS R01 AR072735NIBIB NIH HHS T32 EB019944NINDS NIH HHS R21 NS104293
6 · The paper itself

Abstract

Unaccustomed resistance exercise can initiate skeletal muscle remodeling and adaptive mechanisms that can confer protection from damage and enhanced strength with subsequent stimulation. The myofiber may provide the primary origin for adaptation, yet multiple mononuclear cell types within the surrounding connective tissue may also contribute. The purpose of this study was to evaluate the acute response of muscle-resident interstitial cells to contraction initiated by electrical stimulation (e-stim) and subsequently determine the contribution of pericytes to remodeling as a result of training. Mice were subjected to bilateral e-stim or sham treatment. Following a single session of e-stim, NG2

Indexed as

AnimalsCD146 AntigenCell DifferentiationCell LineageElectric StimulationMaleMiceMice, Inbred C57BLMuscle ContractionMuscle, SkeletalPericytesCD146 AntigenMcam protein, mouseangiogenesisCD146contractionextracellular matrixfibroadipogenic progenitorpericyteremodelingstem cells

Identifiers

PMID31433691
PMCPMC6879875
OpenAlexW2969857261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.