Evidence map›Paper›PMID 31433614›Full record

ArticleACS infectious diseases2019

Probing the Robustness of Inhibitors of Tuberculosis Aminoglycoside Resistance Enzyme Eis by Mutagenesis.

Keith D Green, Ankita Punetha, Caixia Hou, Sylvie Garneau-Tsodikova, Oleg V Tsodikov

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. NProceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Keith D GreenDepartment of Pharmaceutical Sciences, College of Pharmacy , University of Kentucky , 789 South Limestone Street , Lexington , Kentucky 40536-0596 , United States.
Ankita PunethaDepartment of Pharmaceutical Sciences, College of Pharmacy , University of Kentucky , 789 South Limestone Street , Lexington , Kentucky 40536-0596 , United States.
Caixia HouDepartment of Pharmaceutical Sciences, College of Pharmacy , University of Kentucky , 789 South Limestone Street , Lexington , Kentucky 40536-0596 , United States.
Sylvie Garneau-TsodikovaDepartment of Pharmaceutical Sciences, College of Pharmacy , University of Kentucky , 789 South Limestone Street , Lexington , Kentucky 40536-0596 , United States.ORCID 0000-0002-7961-5555
Oleg V TsodikovDepartment of Pharmaceutical Sciences, College of Pharmacy , University of Kentucky , 789 South Limestone Street , Lexington , Kentucky 40536-0596 , United States.ORCID 0000-0001-7094-4216
University of Kentucky · US

Funding

Novel aminoglycoside adjuvants and stand-alone agents to combat tuberculosisR01AI090048 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GARNEAU-TSODIKOVA, SYLVIE · 2011 to 2021
$4.4M
NIAID NIH HHS R01 AI090048
6 · The paper itself

Abstract

Each year, millions of people worldwide contract tuberculosis (TB), the deadliest infection. The spread of infections with drug-resistant strains of

Indexed as

MutagenesisAcetylationAcetyltransferasesAminoglycosidesAntigens, BacterialAntitubercular AgentsBacterial ProteinsBinding SitesDrug Resistance, BacterialEnzyme InhibitorsKanamycinKineticsModels, MolecularMutationMycobacterium tuberculosisProtein ConformationAcetyltransferasesAminoglycosidesAntigens, BacterialAntitubercular AgentsBacterial ProteinsEis protein, Mycobacterium tuberculosisEnzyme InhibitorsKanamycinacetylationenzyme inhibitorkanamycinmutationsmycobacteria

Identifiers

PMID31433614
PMCPMC7337102
OpenAlexW2969597976

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.