Evidence map›Paper›PMID 31433299›Full record

ArticleeLife2019

Subtle selectivity in a pheromone sensor triumvirate desynchronizes competence and predation in a human gut commensal.

Johann Mignolet, Guillaume Cerckel, Julien Damoczi, Laura Ledesma-Garcia, Andrea Sass, Tom Coenye, Sylvie Nessler, Pascal Hols

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  3. Review
  4. Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Johann MignoletBiochemistry and Genetics of Microorganisms (BGM), Louvain Institute of Biomolecular Science and Technology, Université catholique de Louvain, Louvain-la-Neuve, Belgium.ORCID 0000-0002-3721-4307
Guillaume Cerckel *Biochemistry and Genetics of Microorganisms (BGM), Louvain Institute of Biomolecular Science and Technology, Université catholique de Louvain, Louvain-la-Neuve, Belgium.
Julien Damoczi *Biochemistry and Genetics of Microorganisms (BGM), Louvain Institute of Biomolecular Science and Technology, Université catholique de Louvain, Louvain-la-Neuve, Belgium.
Laura Ledesma-GarciaBiochemistry and Genetics of Microorganisms (BGM), Louvain Institute of Biomolecular Science and Technology, Université catholique de Louvain, Louvain-la-Neuve, Belgium.
Andrea SassLaboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium.
Tom CoenyeLaboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium.
Sylvie NesslerInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
Pascal HolsBiochemistry and Genetics of Microorganisms (BGM), Louvain Institute of Biomolecular Science and Technology, Université catholique de Louvain, Louvain-la-Neuve, Belgium.

Funding

BELSPO Project P7/28Fonds De La Recherche Scientifique - FNRS PDR T.0110.18-FWalloon Region (Belgium) RPR1620203
6 · The paper itself

Abstract

Constantly surrounded by kin or alien organisms in nature, eukaryotes and prokaryotes developed various communication systems to coordinate adaptive multi-entity behavior. In complex and overcrowded environments, they require to discriminate relevant signals in a myriad of pheromones to execute appropriate responses. In the human gut commensal

Indexed as

Gastrointestinal MicrobiomeMicrobiotaAnti-Bacterial AgentsBacterial ProteinsBacteriocinsDNA Transformation CompetenceGene Expression Regulation, BacterialGene Regulatory NetworksHumansPheromonesStreptococcus salivariusAnti-Bacterial AgentsBacterial ProteinsBacteriocinsPheromonesbacteriocinbiochemistrycell-cell communicationchemical biologycompetenceinfectious diseasemicrobiologypredationRNPPStreptococcus salivarius

Identifiers

PMID31433299
PMCPMC6703854

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.