Evidence map›Paper›PMID 31433284›Full record

ArticleHealth security

STEM: An Open Source Tool for Disease Modeling.

Judith V Douglas, Simone Bianco, Stefan Edlund, Tekla Engelhardt, Matthias Filter, Taras Günther, Kun Maggie Hu, Emily J Nixon, Nereyda L Sevilla, Ahmad Swaid and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Health security. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 5 countries.

Judith V DouglasJudith V. Douglas, MHS, was Lead Technical Writer, Science to Solutions; Simone Bianco, PhD, is a Research Staff Member, Industrial and Applied Genomics, Science to Solutions; Stefan Edlund, MS, is a Research Software Engineer, Industrial and Applied Genomics, Science to Solutions; Kun (Maggie) Hu, PhD, is Research Manager, Public Health and Food Safety; and James H. Kaufman, PhD, is Chief Scientist, Science to Solutions; all at IBM Research-Almaden, San Jose, CA.
Simone BiancoJudith V. Douglas, MHS, was Lead Technical Writer, Science to Solutions; Simone Bianco, PhD, is a Research Staff Member, Industrial and Applied Genomics, Science to Solutions; Stefan Edlund, MS, is a Research Software Engineer, Industrial and Applied Genomics, Science to Solutions; Kun (Maggie) Hu, PhD, is Research Manager, Public Health and Food Safety; and James H. Kaufman, PhD, is Chief Scientist, Science to Solutions; all at IBM Research-Almaden, San Jose, CA.
Stefan EdlundJudith V. Douglas, MHS, was Lead Technical Writer, Science to Solutions; Simone Bianco, PhD, is a Research Staff Member, Industrial and Applied Genomics, Science to Solutions; Stefan Edlund, MS, is a Research Software Engineer, Industrial and Applied Genomics, Science to Solutions; Kun (Maggie) Hu, PhD, is Research Manager, Public Health and Food Safety; and James H. Kaufman, PhD, is Chief Scientist, Science to Solutions; all at IBM Research-Almaden, San Jose, CA.
Tekla EngelhardtTekla Engelhardt, PhD, is an Analyst, System Management and Supervision Directorate, National Food Chain Safety Office, Budapest, Hungary.
Matthias FilterMatthias Filter, Dipl, is a Research Scientist; Taras Günther, MSc, is a PhD student and Scientific Assistant; and Ahmad Swaid is a Software Developer; all in the Biological Safety Department, Food Hygiene and Technology, Supply Chains and Food Defense, German Federal Institute for Risk Assessment, Berlin, Germany.
Taras GüntherJudith V. Douglas, MHS, was Lead Technical Writer, Science to Solutions; Simone Bianco, PhD, is a Research Staff Member, Industrial and Applied Genomics, Science to Solutions; Stefan Edlund, MS, is a Research Software Engineer, Industrial and Applied Genomics, Science to Solutions; Kun (Maggie) Hu, PhD, is Research Manager, Public Health and Food Safety; and James H. Kaufman, PhD, is Chief Scientist, Science to Solutions; all at IBM Research-Almaden, San Jose, CA.
Kun Maggie HuJudith V. Douglas, MHS, was Lead Technical Writer, Science to Solutions; Simone Bianco, PhD, is a Research Staff Member, Industrial and Applied Genomics, Science to Solutions; Stefan Edlund, MS, is a Research Software Engineer, Industrial and Applied Genomics, Science to Solutions; Kun (Maggie) Hu, PhD, is Research Manager, Public Health and Food Safety; and James H. Kaufman, PhD, is Chief Scientist, Science to Solutions; all at IBM Research-Almaden, San Jose, CA.
Emily J NixonEmily J. Nixon is a PhD student, School of Biological Sciences, University of Bristol, UK.
Nereyda L SevillaNereyda L. Sevilla, PhD, is an Aerospace Physiologist, Schar School of Policy and Government, George Mason University, Fairfax, VA.
Ahmad SwaidJudith V. Douglas, MHS, was Lead Technical Writer, Science to Solutions; Simone Bianco, PhD, is a Research Staff Member, Industrial and Applied Genomics, Science to Solutions; Stefan Edlund, MS, is a Research Software Engineer, Industrial and Applied Genomics, Science to Solutions; Kun (Maggie) Hu, PhD, is Research Manager, Public Health and Food Safety; and James H. Kaufman, PhD, is Chief Scientist, Science to Solutions; all at IBM Research-Almaden, San Jose, CA.
James H KaufmanJudith V. Douglas, MHS, was Lead Technical Writer, Science to Solutions; Simone Bianco, PhD, is a Research Staff Member, Industrial and Applied Genomics, Science to Solutions; Stefan Edlund, MS, is a Research Software Engineer, Industrial and Applied Genomics, Science to Solutions; Kun (Maggie) Hu, PhD, is Research Manager, Public Health and Food Safety; and James H. Kaufman, PhD, is Chief Scientist, Science to Solutions; all at IBM Research-Almaden, San Jose, CA.
Health Solutions (Sweden) · SEFederal Institute for Risk Assessment · DEGeorge Mason University · USNational Food Chain Safety Office · HUSan Francisco Foundation · USUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Spatiotemporal Epidemiologic Modeler (STEM) is an open source software project supported by the Eclipse Foundation and used by a global community of researchers and public health officials working to track and, when possible, control outbreaks of infectious disease in human and animal populations. STEM is not a model or a tool designed for a specific disease; it is a flexible, modular framework supporting exchange and integration of community models, reusable plug-in components, and denominator data, available to researchers worldwide at www.eclipse.org/stem. A review of multiple projects illustrates its capabilities. STEM has been used to study variations in transmission of seasonal influenza in Israel by strains; evaluate social distancing measures taken to curb the H1N1 epidemic in Mexico City; study measles outbreaks in part of London and inform local policy on immunization; and gain insights into H7N9 avian influenza transmission in China. A multistrain dengue fever model explored the roles of the mosquito vector, cross-strain immunity, and antibody response in the frequency of dengue outbreaks. STEM has also been used to study the impact of variations in climate on malaria incidence. During the Ebola epidemic, a weekly conference call supported the global modeling community; subsequent work modeled the impact of behavioral change and tested disease reintroduction via animal reservoirs. Work in Germany tracked salmonella in pork from farm to fork; and a recent doctoral dissertation used the air travel feature to compare the potential threats posed by weaponizing infectious diseases. Current projects include work in Great Britain to evaluate control strategies for parasitic disease in sheep, and in Germany and Hungary, to validate the model and inform policy decisions for African swine fever. STEM Version 4.0.0, released in early 2019, includes tools used in these projects and updates technical aspects of the framework to ease its use and re-use.

Indexed as

AnimalsCommunicable Diseases, EmergingDisease OutbreaksHemorrhagic Fever, EbolaHumansInfluenza, HumanPopulation SurveillancePublic HealthSoftwareEpidemic management/responseInfectious diseasesInfluenzaOpen source epidemiologic modelingViral hemorrhagic fevers

Identifiers

PMID31433284
PMCPMC6708268
OpenAlexW2969595333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.