ArticleMacromolecular bioscience2020
3D Printing of Silk Protein Structures by Aqueous Solvent-Directed Molecular Assembly.
Article in Macromolecular bioscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Engineering conformational transitions in silk fibroin hydrogels to create advanced dynamic microenvironments for biomedical applications.Regenerative biomaterials · 2026Review
- Microstructured silk fiber scaffolds with enhanced stretchability.Biomaterials science · 2024Article
- Silk fibroin-based inks forBioactive materials · 2024Article
- Silk Fibroin Materials: Biomedical Applications and Perspectives.Bioengineering (Basel, Switzerland) · 2024Review
- Advanced Applications of Silk-Based Hydrogels for Tissue Engineering: A Short Review.Biomimetics (Basel, Switzerland) · 2023Review
- Silk fibroin, gelatin, and human placenta extracellular matrix-based composite hydrogels for 3D bioprinting and soft tissue engineering.Biomaterials research · 2023Article
- [Research progress on bioactive strategies for promoting tendon graft healing after anterior cruciate ligament reconstruction].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023Review
- Building Blood Vessel Chips with Enhanced Physiological Relevance.Advanced materials technologies · 2023Article
- Volumetric additive manufacturing of pristine silk-based (bio)inks.Nature communications · 2023Article
- A brief review on the mechanisms and approaches of silk spinning-inspired biofabrication.Frontiers in bioengineering and biotechnology · 2023Review
- 3D Printing of Monolithic Proteinaceous Cantilevers Using Regenerated Silk Fibroin.Molecules (Basel, Switzerland) · 2022Article
- Processing-Structure-Properties Relationships of Glycerol-Plasticized Silk Films.Molecules (Basel, Switzerland) · 2022Article
- Conformation-driven strategy for resilient and functional protein materials.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Fiber-Based Biopolymer Processing as a Route toward Sustainability.Advanced materials (Deerfield Beach, Fla.) · 2022Review
- Deconstruction and Reassembly of Renewable Polymers and Biocolloids into Next Generation Structured Materials.Chemical reviews · 2021Review
- 3D electron-beam writing at sub-15 nm resolution using spider silk as a resist.Nature communications · 2021Article
- In Situ 3D Printing: Opportunities with Silk Inks.Trends in biotechnology · 2021Review
- Recent Advances in 3D Printing with Protein-Based Inks.Progress in polymer science · 2021Article
- Recent progress in silk fibroin-based flexible electronics.Microsystems & nanoengineering · 2021Review
- Photo-Crosslinked Silk Fibroin for 3D Printing.Polymers · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
Hierarchical molecular assembly is a fundamental strategy for manufacturing protein structures in nature. However, to translate this natural strategy into advanced digital manufacturing like three-dimensional (3D) printing remains a technical challenge. This work presents a 3D printing technique with silk fibroin to address this challenge, by rationally designing an aqueous salt bath capable of directing the hierarchical assembly of the protein molecules. This technique, conducted under aqueous and ambient conditions, results in 3D proteinaceous architectures characterized by intrinsic biocompatibility/biodegradability and robust mechanical features. The versatility of this method is shown in a diversity of 3D shapes and a range of functional components integrated into the 3D prints. The manufacturing capability is exemplified by the single-step construction of perfusable microfluidic chips which eliminates the use of supporting or sacrificial materials. The 3D shaping capability of the protein material can benefit a multitude of biomedical devices, from drug delivery to surgical implants to tissue scaffolds. This work also provides insights into the recapitulation of solvent-directed hierarchical molecular assembly for artificial manufacturing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.