Evidence map›Paper›PMID 31433077›Full record

ArticleMagnetic resonance in medicine2020

Perfusion and apparent oxygenation in the human placenta (PERFOX).

Jana Hutter, Anita A Harteveld, Laurence H Jackson, Suzanne Franklin, Clemens Bos, Matthias J P van Osch, Jonathan O'Muircheartaigh, Alison Ho, Lucy Chappell, Joseph V Hajnal and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Toward Clinical Implementation of Magnetic Resonance Imaging for Placental Function.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Developments in functional imaging of the placenta.The British journal of radiology · 2023
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Observational
  17. The application ofJournal of developmental origins of health and disease · 2021
    Review
  18. Article
  19. Article
  20. Placentation in the Human and Higher Primates.Advances in anatomy, embryology, and cell biology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Jana HutterCentre for the Developing Brain, King's College London, London, United Kingdom.ORCID 0000-0003-3476-3500
Anita A HarteveldDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Laurence H JacksonCentre for the Developing Brain, King's College London, London, United Kingdom.ORCID 0000-0002-5904-8012
Suzanne FranklinC.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-6886-5578
Clemens BosDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Matthias J P van OschC.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-7034-8959
Jonathan O'MuircheartaighCentre for the Developing Brain, King's College London, London, United Kingdom.
Alison HoAcademic Women's Health Department, King's College London, London, United Kingdom.
Lucy ChappellAcademic Women's Health Department, King's College London, London, United Kingdom.
Joseph V HajnalCentre for the Developing Brain, King's College London, London, United Kingdom.
Mary RutherfordCentre for the Developing Brain, King's College London, London, United Kingdom.
Enrico De VitaSchool of Medical Engineering, King's College London, London, United Kingdom.
King's College London · GBLeiden University Medical Center · NLUniversity Medical Center Utrecht · NL

Funding

Structure and function of the placenta from implantation to delivery: a next generation MRI approachU01HD087202 · NICHD · KING'S COLLEGE LONDON · PI ALEXANDER, DANIEL, ALJABAR, PAUL · 2015 to 2015
$3.2M
Department of Health RP-2014-05-019NICHD NIH HHS U01 HD087202Wellcome Trust 201374Wellcome Trust 201374/Z/16/ZWellcome Trust 203148
6 · The paper itself

Abstract

purposeTo study placental function-both perfusion and an oxygenation surrogate (

methodsFifteen pregnant women were scanned on a 3T MR scanner. For perfusion measurements, a velocity selective arterial spin labeling preparation module was placed before a multi-echo gradient echo EPI readout to integrate

resultsThe optimized integrated PERFOX protocol and post-processing allowed successful visualization and quantification of perfusion and

conclusionsA strength of the joint sequence is that it provides truly simultaneous and co-registered estimates of local

Indexed as

Echo-Planar ImagingMagnetic Resonance ImagingAlgorithmsBlood CirculationContrast MediaFemaleFourier AnalysisGestational AgeHumansImage EnhancementImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMagnetic Resonance AngiographyMotionOxygenPerfusionContrast MediaOxygenSpin LabelsArterial Spin Labeling (ASL)perfusionplacentapre-eclampsiarelaxometryvelocity-selective ASL

Identifiers

PMID31433077
PMCPMC6825519
OpenAlexW2950520565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.