ArticleIET nanobiotechnology2019
Putative mechanism for anticancer properties of Ag-PP (NPs) extract.
Article in IET nanobiotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Nanomaterial-mediated multidimensional regulation of the bone microenvironment: a precise therapeutic strategy for bone metabolic imbalance.Drug delivery · 2025Review
- Nebulized Hybrid Nanoarchaeosomes: Anti-Inflammatory Activity, Anti-Microbial Activity and Cytotoxicity on A549 Cells.International journal of molecular sciences · 2025Article
- Bioinspired multifunctional silver nanoparticles by Smilax Chenensis and their enhanced biomedical and catalytic applications.Scientific reports · 2024Article
- Anti-proliferative activity of chitosan-coated oxypeucedanin nano-chitosomes (COPD-NCs) against human HT-29 colon cancer cells: in vitro study.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
- Silver Nanoparticles as an Intracanal Medicament: A Scoping Review.TheScientificWorldJournal · 2023Article
- Microvascular Experimentation in the Chick Chorioallantoic Membrane as a Model for Screening Angiogenic Agents including from Gene-Modified Cells.International journal of molecular sciences · 2021Review
- Hyaluronic Acid-Silver Nanocomposites and Their Biomedical Applications: A Review.Materials (Basel, Switzerland) · 2021Review
- Silver nanoparticles: Synthesis, medical applications and biosafety.Theranostics · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the most important challenges in treating cancer is the invasion and the angiogenesis of cancer cells. The synthesis of green nanoparticles (NPs) and their use in therapeutic fields is one of the most effective methods with minimal side effects in cancer treatment. In this study, cytotoxic and anti-angiogenic effects of silver NPs (AgNPs) coated with palm pollen extract [Ag-PP(NPs)] were evaluated. For this purpose, the cells were treated with NPs and then were subjected to trypan blue testing (48 h). Then, the cancer invasion was evaluated by the scratch procedure and the expressions of the vascular endothelial growth factor (VEGF) and its receptor (VEGF-R) genes were estimated using real-time PCR assay. Also, the angiogenesis effect of the NPs was investigated with chick chorioallantoic membrane (CAM) assay. The Ag-PP(NPs) induced cytotoxicity on MCF7 cells. The findings also showed that Ag-PP(NPs) inhibit invasive cancer cells and reduce the expression of VEGF and VEGF-R and significantly reduced the number and vessels lengths and the lengths and weights of the embryos in CAM assay. Ag-PP(NPs) with the induction of cytotoxic effects, metastatic inhibition and anti-angiogenesis properties should be considered as an appropriate option for treatment of cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.