Evidence map›Paper›PMID 31432740›Full record

ArticleRNA biology2019

Identification of the Selenoprotein S Positive UGA Recoding (SPUR) element and its position-dependent activity.

Eric M Cockman, Vivek Narayan, Belinda Willard, Sumangala P Shetty, Paul R Copeland, Donna M Driscoll

Open access · hybridAbstract read
In one paragraph

Article in RNA biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Selenoprotein K at the intersection of cellular pathways.Archives of biochemistry and biophysics · 2025
    Review
  2. Review
  3. Selenoprotein S: A versatile disordered protein.Archives of biochemistry and biophysics · 2022
    Review
  4. Article
  5. Article
  6. Ribosome Fate during Decoding of UGA-Sec Codons.International journal of molecular sciences · 2021
    Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Eric M CockmanDepartment of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Vivek NarayanDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA.
Belinda WillardDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA.
Sumangala P ShettyDepartment of Biochemistry and Molecular Biology, Rutgers University, New Brunswick, NJ, USA.
Paul R CopelandDepartment of Biochemistry and Molecular Biology, Rutgers University, New Brunswick, NJ, USA.
Donna M DriscollDepartment of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Cleveland Clinic · USRutgers, The State University of New Jersey · USCase Western Reserve University · US

Funding

Functional Analysis of SBP2 and Selenocysteine IncorporationR01GM077073 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI COPELAND, PAUL R · 2006 to 2022
$5.5M
A cis-acting code in selenoprotein mRNAs dictates selenocysteine incorporationR01DK107426 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI DRISCOLL, DONNA M · 2016 to 2019
$1.4M
High-End Instrumentation (HEI) Grant Program (S10)S10OD023436 · OD · CLEVELAND CLINIC LERNER COM-CWRU · PI WILLARD, BELINDA BELLE · 2017 to 2017
$873k
NIDDK NIH HHS R01 DK107426NIGMS NIH HHS R01 GM077073NIH HHS S10 OD023436
6 · The paper itself

Abstract

Selenoproteins are a unique class of proteins that contain the 21

Indexed as

Biological AssayInverted Repeat SequencesPeptide Chain Termination, Translational3' Untranslated RegionsAnimalsCell Line, TumorCodon, TerminatorConserved SequenceHEK293 CellsHepatocytesHumansMass SpectrometryNucleic Acid ConformationPoint MutationRatsSelenocysteine3' Untranslated RegionsCodon, TerminatorSelenocysteineSelenoproteins3′ untranslated regionmRNA translationselenocysteineSelenoproteinsSelenoprotein S

Identifiers

PMID31432740
PMCPMC6844570
OpenAlexW2969379262

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.