Evidence map›Paper›PMID 31432708›Full record

ArticleAmerican journal of physiology. Renal physiology2019

Rho kinase inhibitors reduce voltage-dependent Ca

Zhengrong Guan, Joshua J Baty, Shali Zhang, Colton E Remedies, Edward W Inscho

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Purinergic P2XAmerican journal of physiology. Renal physiology · 2020
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zhengrong GuanDivision of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Joshua J BatyDivision of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Shali ZhangDivision of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Colton E RemediesDivision of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Edward W InschoDivision of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
University of Alabama at Birmingham · US

Funding

Renal endothelin receptor-specific function in angiotensin ll-dependent hypertensP01HL095499 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI POLLOCK, DAVID M · 2010 to 2014
$11.1M
TLR4 in the Regulation of Renal Microvascular FunctionR01DK044628 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI INSCHO, EDWARD W · 2000 to 2021
$6.2M
Sphingosine-1-phosphate in renal microvascular dysfunction of ischemia-reperfusion kidney injuryR01DK106500 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUAN, ZHENGRONG · 2017 to 2020
$1.4M
PURINERGIC REGULATION OF THE RENAL MICROVASCULATURER29DK044628 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI INSCHO, EDWARD W. · 1994 to 1998
–
NHLBI NIH HHS P01 HL095499NIDDK NIH HHS R01 DK044628NIDDK NIH HHS R01 DK106500NIDDK NIH HHS R29 DK044628
6 · The paper itself

Abstract

Voltage-dependent L-type Ca

Indexed as

3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl esterAmidesAnimalsAortaArteriolesBacterial ProteinsCalcium ChannelsCell LineKidneyMaleMyocytes, Smooth MusclePotassium ChloridePyridinesRatsRepressor Proteinsrho-Associated Kinases3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl esterAmidesBacterial ProteinsCalcium ChannelsPotassium ChloridePyridinesRepressor Proteinsrho-Associated KinasesRKI-1447SprA protein, Salmonella typhimuriumThiazolesUreaY 27632afferent arterioleBay K8644calcium signalingRKI-1447voltage-dependent L-type Ca2+ channelsY-27632

Identifiers

PMID31432708
PMCPMC6879933
OpenAlexW2969331903

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.