Evidence map›Paper›PMID 31432635›Full record

ArticleAnnals of laboratory medicine2020

Adjustment of Modified Carbapenem Inactivation Method Conditions for Rapid Detection of Carbapenemase-Producing

Thao Nguyen Vu, Jung Hyun Byun, Roshan D'Souza, Naina Adren Pinto, Le Phuong Nguyen, Dongeun Yong, Yunsop Chong

Abstract read
In one paragraph

Article in Annals of laboratory medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Molecular and clinical epidemiology of carbapenem resistantThe Lancet regional health. Western Pacific · 2024
    Article
  7. Article
  8. Environmental contamination with carbapenem resistantFrontiers in cellular and infection microbiology · 2024
    Article
  9. Molecular and clinical epidemiology of carbapenem resistantThe Lancet regional health. Western Pacific · 2023
    Article
  10. Article
  11. A Variant Carbapenem Inactivation Method (CIM) forPathogens (Basel, Switzerland) · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thao Nguyen VuDepartment of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7393-745X
Jung Hyun ByunDepartment of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5909-5807
Roshan D'SouzaDepartment of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6576-7574
Naina Adren PintoDepartment of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8348-8990
Le Phuong NguyenDepartment of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-6123-5426
Dongeun YongDepartment of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-1225-8477
Yunsop ChongDepartment of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-6754-6073

Funding

BioNano Health Guard Research Center H-GUARD_2014M3A6B2060509Korea Health Industry Development Institute HI17C1807National Research Foundation of Korea 2017M3A7B4039936Yonsei University
6 · The paper itself

Abstract

backgroundThe existing modified carbapenem inactivation methods (mCIMs) recommended by the CLSI for detecting carbapenemase production have not been applicable for

methodsSeventy-three

resultsThe matrices had an impact on the stability of the MEM disk after the incubation period (two or four hrs). TSB nutrient broth is an appropriate matrix for mCIM compared with Tris-HCl pH 7.6, which leads to the loss of MEM activity in CIMTris. The sensitivity and the specificity of the optimal mCIM were both 100%.

conclusionsWe established optimal mCIM conditions for simple, accurate, and reproducible detection of carbapenemase-producing

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesDisk Diffusion Antimicrobial TestsDrug Resistance, BacterialMeropenemAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseMeropenemAcinetobacter baumanniiCarbapenemaseCIMTrisModified carbapenem inactivation method

Identifiers

PMID31432635
PMCPMC6713649

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.