Evidence map›Paper›PMID 31432397›Full record

ArticleIrish journal of medical science2020

The prevalence and incidence of thyroid dysfunction in patients with diabetes - a longitudinal follow-up study.

Roxana Maria Tudor, Aoife Garrahy, Conor P Woods, Rachel K Crowley, William T Tormey, Diarmuid Smith, Mensud Hatunic, Christopher J Thompson

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Article in Irish journal of medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Roxana Maria TudorAcademic Department of Diabetes and Endocrinology, Beaumont Hospital/RCSI, Medical School Dublin, Dublin 9, Ireland.ORCID http://orcid.org/0000-0002-4538-6010
Aoife GarrahyAcademic Department of Diabetes and Endocrinology, Beaumont Hospital/RCSI, Medical School Dublin, Dublin 9, Ireland.
Conor P WoodsAcademic Department of Diabetes and Endocrinology, Beaumont Hospital/RCSI, Medical School Dublin, Dublin 9, Ireland.
Rachel K CrowleyAcademic Department of Diabetes and Endocrinology, Beaumont Hospital/RCSI, Medical School Dublin, Dublin 9, Ireland.
William T TormeyDepartment of Chemical Pathology, Beaumont Hospital/RCSI Medical School Dublin, Dublin 9, Ireland.
Diarmuid SmithAcademic Department of Diabetes and Endocrinology, Beaumont Hospital/RCSI, Medical School Dublin, Dublin 9, Ireland.
Mensud HatunicAcademic Department of Diabetes and Endocrinology, Beaumont Hospital/RCSI, Medical School Dublin, Dublin 9, Ireland.
Christopher J ThompsonAcademic Department of Diabetes and Endocrinology, Beaumont Hospital/RCSI, Medical School Dublin, Dublin 9, Ireland. christhompson@beaumont.ie.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThyroid dysfunction (TD) occurs in 13.4% of diabetic patients, which has prompted recommendations for annual thyroid screening in patients with diabetes. However, recommendations for annual screening should be based on disease incidence rather than prevalence.

methodsIn 1997-1998, seven hundred and thirty patients (618 type 2 diabetes, 55% male; 112 type 1 diabetes, 47% male) were sequentially screened for TD. The 639 patients with normal thyroid function were followed from 1999 to 2006, with annual thyroid function tests.

resultsA total of 21/112 (19%) with type 1 diabetes (T1DM) and 70/618 (11%) with type 2 diabetes (T2DM) had TD. TD was more frequent in females (p < 0.05) and T1DM (p = 0.04). The mean annual rate of conversion to abnormal tests was 2.1%. At 8 years, there were 100 new cases of TD representing 15.6% of the cohort (17 T1DM and 83 T2DM). TD was more frequent in females (p < 0.05), but there was no difference in the incidence of new TD between T1DM and T2DM (p = 0.39).

conclusionsOur data confirms the high prevalence of TD in diabetic patients, in concordance with the results from other series. We found only 25 treatable cases of new thyroid disease from 639 patients in the 8-year follow-up, less than 0.5% per year. The low incidence of treatable thyroid disease challenges the need for annual screening for thyroid abnormalities in patients with type 2 diabetes.

Indexed as

AdultAgedAged, 80 and overCohort StudiesDiabetes Mellitus, Type 2FemaleFollow-Up StudiesHumansIncidenceLongitudinal StudiesMaleMiddle AgedPrevalenceThyroid DiseasesYoung AdultDiabetes mellitusIncidencePrevalenceThyroid diseaseThyroid dysfunction

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.