Evidence map›Paper›PMID 31432358›Full record

ArticleMolecular biology reports2019

Consistent production of kojic acid from Aspergillus sojae SSC-3 isolated from rice husk.

Shifali Chib, Ashish Dogra, Utpal Nandi, Saurabh Saran

Abstract read
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In one paragraph

Article in Molecular biology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Fungal production of kojic acid and its industrial applications.Applied microbiology and biotechnology · 2023
    Review
  4. Review
  5. Article
  6. Food science and biotechnology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shifali ChibFermentation Technology Division, CSIR- Indian Institute of Integrative Medicine, Canal Road, Jammu, 180001, India.
Ashish DograPK-PD, Toxicology and Formulation Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu, 180001, India.
Utpal NandiPK-PD, Toxicology and Formulation Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu, 180001, India.
Saurabh SaranFermentation Technology Division, CSIR- Indian Institute of Integrative Medicine, Canal Road, Jammu, 180001, India. ssaran@iiim.ac.in.ORCID http://orcid.org/0000-0002-9841-7343

Funding

Department of Science and Technology (IN) EMR/2016/002786
6 · The paper itself

Abstract

A consistent kojic acid producing fungal strain has been isolated from rice husk using glucose-peptone medium. The isolate was identified as Aspergillus sojae SSC-3 on 18S rDNA analysis. A. sojae was capable of producing substantially good amount of kojic acid, however the production was varying from batch to batch. In order to obtain consistent, repeated and high levels of kojic acid, monospore isolation procedures was adopted. The highest production of kojic acid obtained was 12 ± 2 g/L in 120 h with sucrose (10%) and yeast extract (0.5%) as carbon and nitrogen source respectively. The process was scale up to 10 L fermenter size which repeatedly resulted in the production of 18 ± 2 g/L of kojic acid in 96 h. Kojic acid was recovered (> 82%) from the fermentation broth with > 99% purity. Best to our knowledge this is the first report were kojic acid production is reported from Aspergillus sojae strain.

Indexed as

AspergillusCarbonFermentationGlucoseNitrogenOryzaPeptonesPyronesSucroseCarbonGlucosekojic acidNitrogenPeptonesPyronesSucroseFermenterFungiKojic acidMonospore screening

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.