ArticleInternational ophthalmology2020
Choroidal thickness in keratoconus.
Article in International ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Quantitative evaluation of choroidal thickness and vascularity in subclinical keratoconus: a cross-sectional EDI-OCT study.International ophthalmology · 2026Article
- Assessment of choroidal vascularity and thickness after corneal crosslinking treatment in keratoconus.BMC ophthalmology · 2026Article
- Macular Choroidal Thickness in Keratoconus: Systematic Review and Meta-Analysis of Current Evidence.Diagnostics (Basel, Switzerland) · 2025Review
- Pachychoroid pigment epitheliopathy in keratoconic eyes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Observational
- Quantifying choroidal and retinal thicknesses variations via optical coherence tomography in different stages of pediatric keratoconus.BMC ophthalmology · 2024Article
- Is there a relationship between the keratoconus and the peripapillary choroidal vasculature?International ophthalmology · 2024Article
- Subfoveal choroidal thickness increases after excimer laser-assisted penetrating keratoplasty but not after excimer laser-assisted deep anterior lamellar keratoplasty.Scientific reports · 2024Article
- Subfoveal and Parafoveal Choroidal Thickening in Patients with Keratoconus Using the ETDRS Grid on Swept-Source OCT.Ophthalmology and therapy · 2024Article
- Serum inflammatory biomarkers are associated with increased choroidal thickness in keratoconus.Scientific reports · 2023Article
- Choroidal thickness assessment in keratoconus patients treated with cross-linking compared to healthy population.International ophthalmology · 2023Observational
- Article
- Assessment of the Retinal Vessels in Keratoconus: An OCT Angiography Study.Journal of clinical medicine · 2022Article
- The Role of Atopy in the Choroidal Profile of Keratoconus Patients.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Increased choroidal thickness is not a disease progression marker in keratoconus.Scientific reports · 2020Observational
- Evaluation of Choroidal Vascularity Index in Keratoconus Patients: Does Choroidal Vascularity Change in Keratoconus?Journal of current ophthalmologyArticle
- Posterior segment alterations in keratoconus patients: an updated comprehensive review.Therapeutic advances in ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeKeratoconus is an ectatic eye disease characterized by progressive thinning and steepening of the cornea which leads to irregular astigmatism and visual function loss. Determination of choroidal thickness in keratoconus patients may help us to better understand and manage the keratoconus disease. Choroidal thickness may be a potential marker for disease activity in keratoconus patients. In this study, we aimed to determine choroidal thickness in keratoconus patients and compare the results with the age-matched control group.
methodsThis is a prospective study with a control group. Keratometry and thinnest corneal thickness was measured and recorded in keratoconus patients. Choroidal thickness of all subjects was measured using an optical coherence tomography device (Spectralis OCT, version 6.0, Heidelberg Engineering, Germany) with an enhanced depth imaging mode without pupil dilation. Mean choroidal thickness of keratoconus patients was compared with healthy subjects.
resultsOne hundred and sixty eyes of 80 healthy subjects and 160 eyes of 80 keratoconus patients were included in the study. Mean thinnest corneal thickness of the keratoconus patients was 449.7 ± 3.2 microns. Mean corneal keratometry value and cylindrical refraction error in the keratoconus patients were 53.2 ± 0.2 and 3.3 ± 0.1 diopters, respectively. Mean choroidal thickness was 363.9 ± 59.8 and 328.4 ± 67.2 microns in keratoconus patients and healthy subjects, respectively. There was a very significant difference between keratoconus patients and healthy subjects in terms of choroidal thickness (P = 0.000). There was not a statistically significant correlation between choroidal thickness and thinnest corneal thickness in keratoconus patients (P = 0.814).
conclusionChoroidal thickness was found to be increased in keratoconus patients. Choroidal thickness could potentially become a new clinical marker for disease activity in keratoconus patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.