Evidence map›Paper›PMID 31431825›Full record

ArticleF1000Research2019

Introducing high school students to the Gene Ontology classification system.

Mehek Dedhia, Kenneth Kohetuk, Wim E Crusio, Anna Delprato

Abstract read
In one paragraph

Article in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Mechanism Prediction ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mehek DedhiaBioScience Project, Wakefield, MA, 01880, USA.
Kenneth KohetukSaint Dominic Savio Catholic High School, Austin, TX, 78717, USA.ORCID 0000-0003-1503-5735
Wim E CrusioInstitut de Neurosciences Cognitives et Intégratives d'Aquitaine (UMR 5287), Pessac, France.ORCID 0000-0001-6638-202X
Anna DelpratoBioScience Project, Wakefield, MA, 01880, USA.ORCID 0000-0002-6134-2560

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a tutorial that introduces high school students to the Gene Ontology classification system which is widely used in genomics and systems biology studies to characterize large sets of genes based on functional and structural information. This classification system is a valuable and standardized method used to identify genes that act in similar processes and pathways and also provides insight into the overall architecture and distribution of genes and gene families associated with a particular tissue or disease. By means of this tutorial, students learn how the classification system works through analyzing a gene set using DAVID the Database for Annotation, Visualization and Integrated Discovery that incorporates the Gene Ontology system into its suite of analysis tools. This method of analyzing genes is used by our high school student interns to categorize gene expression data related to behavioral neuroscience. Students will get a feel for working with genes and gene sets, acquire vocabulary, obtain an understanding of how a database is structured and gain an awareness of the vast amount of information that is known about genes as well as the online analysis tools to manage this information that is nowadays available. Based on survey responses, students intellectually benefit from learning about the Gene Ontology System and using the DAVID tools, they are better prepared for future database use and they also find it enjoyable.

Indexed as

Databases, GeneticGene OntologyGenomicsGene ExpressionHumansStudentsgene ontologygenomicshigh school students

Identifiers

PMID31431825
PMCPMC6619382

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.