Evidence map›Paper›PMID 31431806›Full record

ArticleCurrent immunology reviews2019

T Cells in the Female Reproductive Tract Can Both Block and Facilitate HIV Transmission.

Christopher J Miller, Ronald S Veazey

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current immunology reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christopher J MillerProfessor of Pathology, Microbiology, and Immunology, Center for Comparative Medicine.
Ronald S VeazeyProfessor of Pathology and Laboratory Medicine, Tulane University School of Medicine.

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
ZCM:A NOVEL BROAD-SPECTRUM MICROBICIDE FOR SEXUALLY TRANSMITTED INFECTIONSP51RR000164 · NCRR · TULANE UNIVERSITY OF LOUISIANA · PI VEAZEY, RONALD S. · 1985 to 2011
$100.1M
Early Events in Mucosal SIV PathogenesisR01AI084793 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI VEAZEY, RONALD S. · 2009 to 2013
$3.9M
Testing novel microbicide candidates in sustained release formulationsR01AI131433 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI VEAZEY, RONALD S. · 2017 to 2020
$2.6M
NCRR NIH HHS P51 RR000164NIAID NIH HHS R01 AI084793NIAID NIH HHS R01 AI131433NIH HHS P51 OD011104NIH HHS P51 OD011107
6 · The paper itself

Abstract

Because HIV is sexually transmitted, there is considerable interest in defining the nature of anti-HIV immunity in the female reproductive tract (FRT) and in developing ways to elicit antiviral immunity in the FRT through vaccination. Although it is assumed that the mucosal immune system of the FRT is of central importance for protection against sexually transmitted diseases, including HIV, this arm of the immune system has only recently been studied. Here we provide a brief review of the role of T cells in the FRT in blocking and facilitating HIV transmission.

Indexed as

cervixHIVsexually transmitted diseaseT cellvagina

Identifiers

PMID31431806
PMCPMC6701933

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.