Evidence map›Paper›PMID 31431669›Full record

ArticleScientific reports2019

Space-like

Bin Liu, Robert G Hinshaw, Kevin X Le, Mi-Ae Park, Shuyan Wang, Anthony P Belanger, Shipra Dubey, Jeffrey L Frost, Qiaoqiao Shi, Peter Holton and 10 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 75 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

Bin LiuDepartment of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, 02115, USA.
Robert G HinshawDepartment of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, 02115, USA.
Kevin X LeDepartment of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, 02115, USA.
Mi-Ae ParkHarvard Medical School, Boston, MA, 02115, USA.
Shuyan WangDepartment of Radiology, Brigham and Women's Hospital, Boston, MA, 02115, USA.
Anthony P BelangerHarvard Medical School, Boston, MA, 02115, USA.
Shipra DubeyHarvard Medical School, Boston, MA, 02115, USA.
Jeffrey L FrostDepartment of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, 02115, USA.
Qiaoqiao ShiDepartment of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, 02115, USA.
Peter HoltonHarvard Medical School, Boston, MA, 02115, USA.
Lee TrojanczykDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Vladimir ReiserGE Healthcare, Princeton, NJ, 08540, USA.
Paul A JonesGE Healthcare, Chalfont St Giles, HP8 4SP, United Kingdom.ORCID http://orcid.org/0000-0002-8385-1702
William TriggGE Healthcare, Chalfont St Giles, HP8 4SP, United Kingdom.
Marcelo F Di CarliHarvard Medical School, Boston, MA, 02115, USA.
Paul LorelloHarvard Medical School Mouse Behavior Core, Boston, MA, 02115, USA.
Barbara J CaldaroneHarvard Medical School Mouse Behavior Core, Boston, MA, 02115, USA.
Jacqueline P WilliamsDepartment of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.ORCID http://orcid.org/0000-0002-5635-1526
M Kerry O'BanionDepartment of Neuroscience, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Cynthia A LemereDepartment of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, 02115, USA. clemere@bwh.harvard.edu.ORCID http://orcid.org/0000-0002-2983-7870
Brigham and Women's Hospital · USUniversity of Rochester Medical Center · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Space travel will expose people to high-energy, heavy particle radiation, and the cognitive deficits induced by this exposure are not well understood. To investigate the short-term effects of space radiation, we irradiated 4-month-old Alzheimer's disease (AD)-like transgenic (Tg) mice and wildtype (WT) littermates with a single, whole-body dose of 10 or 50 cGy

Indexed as

Space FlightAlzheimer DiseaseAmyloid beta-PeptidesAnimalsBehavior, AnimalBrainDisease Models, AnimalDose-Response Relationship, RadiationFemaleHumansInflammationIron RadioisotopesLearningMaleMice, Inbred C57BLMice, TransgenicAmyloid beta-PeptidesIron RadioisotopesPresenilin-1PSEN1 protein, human

Identifiers

PMID31431669
PMCPMC6702228
OpenAlexW2969331602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.