Evidence map›Paper›PMID 31431667›Full record

ArticleScientific reports2019

The Delta Neutrophil Index Predicts the Development of In-hospital Hypotension in Initially Stable Patients with Pyogenic Liver Abscess.

Taeyoung Kong, Yoo Seok Park, Hye Sun Lee, Sinae Kim, Jong Wook Lee, Je Sung You, Hyun Soo Chung, Incheol Park, Sung Phil Chung

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Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Taeyoung KongDepartment of Emergency Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Yoo Seok ParkDepartment of Emergency Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Hye Sun LeeDepartment of Research Affairs, Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0001-6328-6948
Sinae KimDepartment of Research Affairs, Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jong Wook LeeDepartment of Laboratory Medicine, Konyang University Hospital, Daejeon, Republic of Korea. lee423619@kyuh.ac.kr.
Je Sung YouDepartment of Emergency Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea. youjsmd@yuhs.ac.ORCID http://orcid.org/0000-0002-2074-6745
Hyun Soo ChungDepartment of Emergency Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Incheol ParkDepartment of Emergency Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Sung Phil ChungDepartment of Emergency Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prompt diagnosis and timely treatment are important for reducing morbidity and mortality from pyogenic liver abscess (PLA). The purpose of this study was to investigate the importance of the delta neutrophil index (DNI) reflecting the fraction of immature granulocytes as a predictor of the development of in-hospital hypotension in initially stable patients with PLA. We retrospectively identified 308 consecutive patients (>18 years) who were hemodynamically stable at presentation and diagnosed with PLA in the emergency department (ED) between January 2011 and September 2017. The outcome of interest was in-hospital hypotension 1-24 hours after admission to the ED. A high DNI at ED admission was an independent predictor of the development of in-hospital hypotension in initially stable patients with PLA (odds ratio [OR]: 1.44, 95.0% confidence interval [CI]: 1.06-1.95; P = 0.02). A DNI > 3.3% was associated with in-hospital hypotension at ED admission (OR: 5.37, 95.0% CI: 2.91-9.92; P < 0.001). The development of in-hospital hypotension was associated with an increased risk of 30-day mortality (HR: 8.55, 95.0% CI: 2.57-28.4; P < 0.001). A high DNI independently predicts the development of in-hospital hypotension in initially stable patients with PLA. In-hospital hypotension is associated with an increased risk of 30-day mortality.

Indexed as

AgedEmergency Service, HospitalFemaleHospitalsHumansHypotensionLeukocyte CountLiver Abscess, PyogenicMaleMiddle AgedNeutrophilsRisk Factors

Identifiers

PMID31431667
PMCPMC6702230

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.