Evidence map›Paper›PMID 31431629›Full record

ArticleScientific reports2019

Development of multifunctional Overhauser-enhanced magnetic resonance imaging for concurrent in vivo mapping of tumor interstitial oxygenation, acidosis and inorganic phosphate concentration.

Artem A Gorodetskii, Timothy D Eubank, Benoit Driesschaert, Martin Poncelet, Emily Ellis, Valery V Khramtsov, Andrey A Bobko

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Hypoxia Imaging as a Radiomics Signature in Tumors Using NovelbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Artem A GorodetskiiIn Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, WV, 26506, USA.
Timothy D EubankIn Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, WV, 26506, USA.
Benoit DriesschaertIn Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, WV, 26506, USA.
Martin PonceletIn Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, WV, 26506, USA.
Emily EllisDepartment of Microbiology, Immunology & Cell Biology, West Virginia University School of Medicine, Morgantown, WV, 26506, USA.
Valery V KhramtsovIn Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, WV, 26506, USA. valery.khramtsov@hsc.wvu.edu.
Andrey A BobkoIn Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, WV, 26506, USA. andrey.bobko@hsc.wvu.edu.

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sally Lynn Hodder · 2012 to 2026
$81.0M
WVU Flow Cytometry and Single Cell Core Facility (FCSCCF)P20GM121322 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Paul R Lockman · 2018 to 2026
$22.4M
In vivo monitoring of tumor microenvironment regulation for macrophagesR01CA194013 · NCI · WEST VIRGINIA UNIVERSITY · PI Timothy D Eubank, Valery V Khramtsov · 2015 to 2026
$3.5M
Profiling chemical tumor microenvironment: Application for diagnostics & therapyR01CA192064 · NCI · WEST VIRGINIA UNIVERSITY · PI EUBANK, TIMOTHY D, KHRAMTSOV, VALERY V · 2015 to 2024
$3.4M
Biocompatible Magnetic Resonance Probes for in vivo Concurrent Profiling R00EB023990 · NIBIB · WEST VIRGINIA UNIVERSITY · PI DRIESSCHAERT, BENOIT · 2019 to 2021
$730k
Biocompatible Magnetic Resonance Probes for in vivo Concurrent Profiling of Interstitial Oxygenation, Acidosis and Inorganic Phosphate: Preclinical Application to CancerK99EB023990 · NIBIB · WEST VIRGINIA UNIVERSITY · PI DRIESSCHAERT, BENOIT · 2017 to 2018
$153k
Vesicular transport of the amyloid precursor proteinF32AG023990 · NIA · YALE UNIVERSITY · PI VOLPICELLI-DALEY, LAURA · 2004 to 2006
$142k
NCI NIH HHS R01 CA192064NCI NIH HHS R01 CA194013NIBIB NIH HHS K99 EB023990NIBIB NIH HHS R00 EB023990NIGMS NIH HHS P20 GM121322NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

Tumor oxygenation (pO

Indexed as

Magnetic Resonance ImagingAcidosisAnimalsBreast NeoplasmsContrast MediaDisease Models, AnimalHumansHydrogen-Ion ConcentrationMicePhosphatesTumor HypoxiaContrast MediaPhosphates

Identifiers

PMID31431629
PMCPMC6702349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.