Evidence map›Paper›PMID 31431613›Full record

ArticleBlood cancer journal2019

Inhibition of E-Selectin (GMI-1271) or E-selectin together with CXCR4 (GMI-1359) re-sensitizes multiple myeloma to therapy.

Barbara Muz, Feda Azab, Mark Fiala, Justin King, Daniel Kohnen, William E Fogler, Ted Smith, John L Magnani, Ravi Vij, Abdel Kareem Azab

Open access · goldAbstract readLetter
In one paragraph

Article in Blood cancer journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. E-selectin in vascular pathophysiology.Frontiers in immunology · 2024
    Review
  6. CXC chemokine receptor 4 (CXCR4) blockade in cancer treatment.Journal of cancer research and clinical oncology · 2023
    Review
  7. Article
  8. The biology of E-selectin ligands in leukemogenesis.Advances in cancer research · 2023
    Review
  9. Article
  10. Adhesion molecules in multiple myeloma oncogenesis and targeted therapy.International journal of hematologic oncology · 2022
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Barbara MuzDepartment of Radiation Oncology, Cancer Biology Division, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Feda AzabDepartment of Radiation Oncology, Cancer Biology Division, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Mark FialaDepartment of Medicine, Division of Medical Oncology, Washington University in St. Louis School of Medicine, Saint Louis, MO, USA.
Justin KingDepartment of Medicine, Division of Medical Oncology, Washington University in St. Louis School of Medicine, Saint Louis, MO, USA.
Daniel KohnenDepartment of Medicine, Division of Medical Oncology, Washington University in St. Louis School of Medicine, Saint Louis, MO, USA.
William E FoglerGlycoMimetics Inc., Rockville, MD, USA.
Ted SmithGlycoMimetics Inc., Rockville, MD, USA.
John L MagnaniGlycoMimetics Inc., Rockville, MD, USA.
Ravi VijDepartment of Medicine, Division of Medical Oncology, Washington University in St. Louis School of Medicine, Saint Louis, MO, USA.
Abdel Kareem AzabDepartment of Radiation Oncology, Cancer Biology Division, Washington University in St. Louis School of Medicine, St. Louis, MO, USA. kareem.azab@wustl.edu.
Washington University in St. Louis · USGlycoMimetics (United States) · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
WU-MDACC Inter-Institutional Molecular Imaging CenterP50CA094056 · NCI · WASHINGTON UNIVERSITY · PI KOPAN, RAPHAEL · 2002 to 2016
$26.3M
Project 2 - Radiation-Induced Treatment of Multiple Myeloma using NanoparticlesU54CA199092 · NCI · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2015 to 2019
$11.5M
NCI NIH HHS P30 CA091842NCI NIH HHS P50 CA094056NCI NIH HHS U54 CA199092
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

E-SelectinFemaleHumansMaleMultiple MyelomaReceptors, CXCR4CXCR4 protein, humanE-SelectinReceptors, CXCR4

Identifiers

PMID31431613
PMCPMC6702213
OpenAlexW2969795870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.