Evidence map›Paper›PMID 31431555›Full record

ArticlemBio2019

Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34

Lindsey B Crawford, Patrizia Caposio, Craig Kreklywich, Andrew H Pham, Meaghan H Hancock, Taylor A Jones, Patricia P Smith, Andrew D Yurochko, Jay A Nelson, Daniel N Streblow

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Mouse Models for Human Herpesviruses.Pathogens (Basel, Switzerland) · 2023
    Review
  16. Article
  17. Hematopoietic stem cells and betaherpesvirus latency.Frontiers in cellular and infection microbiology · 2023
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lindsey B CrawfordVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Patrizia CaposioVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Craig KreklywichVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Andrew H PhamVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Meaghan H HancockVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Taylor A JonesVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Patricia P SmithVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Andrew D YurochkoDepartment of Microbiology and Immunology, Louisiana State University at Shreveport, Shreveport, Louisiana, USA.ORCID 0000-0002-6452-5813
Jay A NelsonVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Daniel N StreblowVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA streblow@ohsu.edu.
Oregon Health & Science University · USLouisiana State University in Shreveport · US

Funding

The Administrative CoreP01AI127335 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI Patrizia Caposio · 2017 to 2026
$24.6M
Virology and Vector Production Core CU19AI128741 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI PICKER, LOUIS J. · 2017 to 2021
$11.8M
NIAID NIH HHS P01 AI127335NIAID NIH HHS U19 AI128741
6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) infection of CD34

Indexed as

LigandsAnimalsAntigens, CD34Cell DifferentiationCytomegalovirusGenome, ViralHematopoiesisHematopoietic Stem CellsHost-Pathogen InteractionsHumansMiceReceptors, ChemokineSignal TransductionViral ProteinsVirus ActivationVirus LatencyAntigens, CD34LigandsReceptors, ChemokineUS28 receptor, CytomegalovirusViral Proteinshematopoiesishuman cytomegaloviruslatencyreactivationUS28

Identifiers

PMID31431555
PMCPMC6703429
OpenAlexW2969331232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.