Evidence map›Paper›PMID 31431544›Full record

ArticleScience signaling2019

Dynamics of drug response informs rational combination regimens.

B Bishal Paudel, Vito Quaranta

Abstract readComment
PubMed Publisher
In one paragraph

Article in Science signaling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Application of nanomedicines in tumor immunotherapy.Journal of molecular cell biology · 2025
    Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

B Bishal PaudelDepartment of Biochemistry, Vanderbilt University, Nashville, TN 37232, USA. bishal.paudel@vanderbilt.edu.
Vito QuarantaDepartment of Biochemistry, Vanderbilt University, Nashville, TN 37232, USA.ORCID 0000-0001-7491-8672

Funding

Single-Cell Biology and Data Analysis Shared Resource (SCB-DA SR)U54CA217450 · NCI · VANDERBILT UNIVERSITY · PI WEAVER, ALISSA M · 2018 to 2022
$8.5M
Quantitative Multiscale Imaging to Optimize Cancer Treatment StrategiesR01CA186193 · NCI · VANDERBILT UNIVERSITY · PI QUARANTA, VITO, RERICHA, ERIN C · 2014 to 2019
$3.1M
Phenotype Transitions in Small Cell Lung CancerU01CA215845 · NCI · VANDERBILT UNIVERSITY · PI LOPEZ, CARLOS FEDERICO, QUARANTA, VITO · 2017 to 2021
$2.8M
Image Driven Multi-Scale Modeling to Predict Treatment Response in Breast CancerU01CA174706 · NCI · VANDERBILT UNIVERSITY · PI QUARANTA, VITO, YANKEELOV, THOMAS E · 2013 to 2018
$2.5M
NCI NIH HHS R01 CA186193NCI NIH HHS U01 CA174706NCI NIH HHS U01 CA215845NCI NIH HHS U54 CA217450
6 · The paper itself

Abstract

Metabolic plasticity in cancer has been linked to the development of drug-tolerant populations. In this issue of

Indexed as

NeoplasmsAdaptation, PhysiologicalDrug ToleranceHumansSignal Transduction

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.