ArticlemSystems2019
A Microbiome-Based Index for Assessing Skin Health and Treatment Effects for Atopic Dermatitis in Children.
Article in mSystems, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Precise assessment of facial skin based on multimodal data fusion of the microbiome.Quantitative biology (Beijing, China) · 2026Article
- Environmental and skin-nasal microbiome variation in South African children with atopic dermatitis.BMC microbiology · 2025Article
- Metagenomic Characterization and Comparative Analysis of Removable Denture-Wearing and Non-Denture-Wearing Individuals in Healthy and Diseased Periodontal Conditions.Microorganisms · 2024Article
- Characterization of pathogenic microbiome on removable prostheses with different levels of cleanliness using 2bRAD-M metagenomic sequencing.Journal of oral microbiology · 2024Article
- The inner elbow skin microbiome containsMicrobiome research reports · 2024Article
- Gut Microbiota Analysis and In Silico Biomarker Detection of Children with Autism Spectrum Disorder across Cohorts.Microorganisms · 2023Article
- Gut microbiome predicts selenium supplementation efficiency across different Chinese adult cohorts using hybrid modeling and feature refining.Frontiers in microbiology · 2023Article
- Towards standardized and reproducible research in skin microbiomes.Environmental microbiology · 2022Review
- [The skin microbiome-useful for diagnosis and therapy?]Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2021Review
- Efficacy of Phototherapy With 308-nm Excimer Light for Skin Microbiome Dysbiosis and Skin Barrier Dysfunction in Canine Atopic Dermatitis.Frontiers in veterinary science · 2021Article
- Computational Modeling of the Human Microbiome.Microorganisms · 2020Review
- Applications of Human Skin Microbiota in the Cutaneous Disorders for Ecology-Based Therapy.Frontiers in cellular and infection microbiology · 2020Review
- Method development for cross-study microbiome data mining: Challenges and opportunities.Computational and structural biotechnology journal · 2020Review
- Efficacy ofGut microbesReview
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A quantitative and objective indicator for skin health via the microbiome is of great interest for personalized skin care, but differences among skin sites and across human populations can make this goal challenging. A three-city (two Chinese and one American) comparison of skin microbiota from atopic dermatitis (AD) and healthy pediatric cohorts revealed that, although city has the greatest effect size (the skin microbiome can predict the originated city with near 100% accuracy), a microbial index of skin health (MiSH) based on 25 bacterial genera can diagnose AD with 83 to ∼95% accuracy within each city and 86.4% accuracy across cities (area under the concentration-time curve [AUC], 0.90). Moreover, nonlesional skin sites across the bodies of AD-active children (which include shank, arm, popliteal fossa, elbow, antecubital fossa, knee, neck, and axilla) harbor a distinct but lesional state-like microbiome that features relative enrichment of
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