Evidence map›Paper›PMID 31431504›Full record

ArticleThe Journal of biological chemistry2019

The TOR pathway modulates cytoophidium formation in

Christos Andreadis, Lydia Hulme, Katherine Wensley, Ji-Long Liu

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Cytoophidium complexes resonate with cell fates.Cellular and molecular life sciences : CMLS · 2025
    Article
  3. The Impact of Developmental and Metabolic Cues on Cytoophidium Formation.International journal of molecular sciences · 2024
    Review
  4. Differential Cytoophidium Assembly betweenInternational journal of molecular sciences · 2024
    Article
  5. Review
  6. Connecting Hippo Pathway and Cytoophidia inInternational journal of molecular sciences · 2024
    Article
  7. Article
  8. Article
  9. CTP synthase: the hissing of the cellular serpent.Histochemistry and cell biology · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Christos AndreadisSchool of Life Sciences and Technology, ShanghaiTech University, 201210 Shanghai, China.
Lydia HulmeMRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom.
Katherine WensleyMRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom.
Ji-Long LiuSchool of Life Sciences and Technology, ShanghaiTech University, 201210 Shanghai, China liujl3@shanghaitech.edu.cn jilong.liu@dpag.ox.ac.uk.ORCID 0000-0002-4834-8554
ShanghaiTech University · CNUniversity of Oxford · GB

Funding

Medical Research Council MC_U137788471Medical Research Council MC_UU_12021/3
6 · The paper itself

Abstract

CTP synthase (CTPS) has been demonstrated to form evolutionarily-conserved filamentous structures termed cytoophidia whose exact cellular functions remain unclear, but they may play a role in intracellular compartmentalization. We have previously shown that the mammalian target of rapamycin complex 1 (mTORC1)-S6K1 pathway mediates cytoophidium assembly in mammalian cells. Here, using the fission yeast

Indexed as

Carbon-Nitrogen LigasesCell CompartmentationCRF Receptor, Type 1CytoplasmGene Knockout TechniquesMechanistic Target of Rapamycin Complex 1Mechanistic Target of Rapamycin Complex 2PhosphorylationProtein Serine-Threonine KinasesReceptors, Corticotropin-Releasing HormoneSchizosaccharomycesSchizosaccharomyces pombe ProteinsSignal TransductionTranscription FactorsCarbon-Nitrogen LigasesCRF Receptor, Type 1CTP synthetaseMechanistic Target of Rapamycin Complex 1Mechanistic Target of Rapamycin Complex 2Protein Serine-Threonine KinasesReceptors, Corticotropin-Releasing HormoneSchizosaccharomyces pombe ProteinsSck2 protein, S pombeTranscription FactorsCTP synthasecytoophidiumfission yeastkinase signalingmetabolic regulationnucleotideprotein filamentationpyrimidineSchizosaccharomyces pombesignal transductionsubcellular organelletarget of rapamycin (TOR)TOR complex (TORC)yeastyeast genetics

Identifiers

PMID31431504
PMCPMC6779450
OpenAlexW2969843193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.