Evidence map›Paper›PMID 31431502›Full record

ArticleThe Journal of biological chemistry2019

Angiogenin activates the astrocytic Nrf2/antioxidant-response element pathway and thereby protects murine neurons from oxidative stress.

Trish T Hoang, Delinda A Johnson, Ronald T Raines, Jeffrey A Johnson

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Emerging roles of transfer RNA fragments in the CNS.Brain : a journal of neurology · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Bilirubin and Redox Stress in Age-Related Brain Diseases.Antioxidants (Basel, Switzerland) · 2023
    Review
  15. Review
  16. Emerging biological functions of ribonuclease 1 and angiogenin.Critical reviews in biochemistry and molecular biology · 2022
    Review
  17. Frontiers in neuroscience · 2022
    Article
  18. Article
  19. Peptides Derived from Angiogenin Regulate Cellular Copper Uptake.International journal of molecular sciences · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Trish T HoangDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706.
Delinda A JohnsonSchool of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin 53705.
Ronald T RainesDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706 rtraines@mit.edu.ORCID 0000-0001-7164-1719
Jeffrey A JohnsonSchool of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin 53705 jajohnson@pharmacy.wisc.edu.
University of Wisconsin–Madison · US

Funding

GRADUATE TRAINING IN MOLECULAR BIOSCIENCEST32GM007215 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HULL, CHRISTINA M · 1985 to 2018
$22.5M
Wisconsin Alzheimer's Disease Research CenterP50AG033514 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CHAPPELL, RICHARD J · 2009 to 2018
$16.2M
RIBONUCLEASES IN CANCER THERAPYR01CA073808 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI RAINES, RONALD T · 1997 to 2024
$7.3M
NCI NIH HHS R01 CA073808NIA NIH HHS P50 AG033514NIGMS NIH HHS T32 GM007215
6 · The paper itself

Abstract

The

Indexed as

AnimalsAntioxidant Response ElementsAstrocytesCell LineMiceNeuronsNeuroprotective AgentsNF-E2-Related Factor 2Oxidative StressRibonuclease, PancreaticSignal TransductionangiogeninNeuroprotective AgentsNF-E2-Related Factor 2Ribonuclease, Pancreaticamyotrophic lateral sclerosis (ALS) (Lou Gehrig disease)angiogenin (ANG)astrocytemotor neuronneurodegenerationneuroprotectionnuclear factor 2 (erythroid-derived 2-like factor) (NFE2L2) (Nrf2)oxidative stressribonuclease

Identifiers

PMID31431502
PMCPMC6791309
OpenAlexW2969790734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.