ArticlePediatrics2019
Parenteral Antibiotic Therapy Duration in Young Infants With Bacteremic Urinary Tract Infections.
Article in Pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Evidence-based clinical practice guideline for management of urinary tract infection and primary vesicoureteric reflux.Pediatric nephrology (Berlin, Germany) · 2024Guideline
- Feasibility and clinical outcomes of short-course intravenous antibiotic therapy in neonates under 28 days with urinary tract infection.European journal of pediatrics · 2026Article
- Treatment of Urinary Tract Infections in Neonates and Young Infants: Evidence and Recommendations.Antibiotics (Basel, Switzerland) · 2026Review
- Article
- Oral Cephalexin Population Pharmacokinetics and Target Attainment Analysis in Infants 7-60 Days Old.Journal of the Pediatric Infectious Diseases Society · 2025Article
- Variability in Treatment of UTIs in Children With Genitourinary Anomalies in Children's Hospitals.Hospital pediatrics · 2025Article
- Variability in Invasive Bacterial Infection Proportions Among Febrile Infants Aged 8-90 Days Using Administrative Data.Academic pediatrics · 2025Article
- Outcomes associated with initial narrow-spectrum versus broad-spectrum antibiotics in children hospitalized with urinary tract infections.Journal of hospital medicine · 2024Article
- Association Between Antibiotic Duration and Recurrence of Urinary Tract Infection in the Neonatal Critical Care Unit.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024Article
- Review
- Effects of urinary tract infection during the first years of life in subsequent growth: a nationwide comparative matched cohort study.Translational pediatrics · 2023Article
- Short duration of parenteral antibiotics in infants with urinary tract infections.Paediatrics & child health · 2023Article
- A Comparison of Short Versus Long Course Intravenous Antibiotics When Treating Urinary Tract Infection in Infants <60 Days of Age.Clinical pediatrics · 2023Article
- Article
- Quality indicators for appropriate antibiotic prescribing in urinary tract infections in children.BMC infectious diseases · 2023Review
- Comparison between Short Therapy and Standard Therapy in Pediatric Patients Hospitalized with Urinary Tract Infection: A Single Center Retrospective Analysis.Children (Basel, Switzerland) · 2022Article
- Management of Pediatric Urinary Tract Infections: A Delphi Study.Antibiotics (Basel, Switzerland) · 2022Article
- Practice Summary of Antimicrobial Therapy for Commonly Encountered Conditions in the Neonatal Intensive Care Unit: A Canadian Perspective.Frontiers in pediatrics · 2022Review
- Examination of Complementary Medicine for Treating Urinary Tract Infections Among Pregnant Women and Children.Frontiers in pharmacology · 2022Review
- Opportunities for Stewardship in the Transition From Intravenous to Enteral Antibiotics in Hospitalized Pediatric Patients.Journal of hospital medicine · 2021Article
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Authors and funding
17 authors at 12 institutions in 1 country.
Funding
Abstract
objectivesTo determine the association between parenteral antibiotic duration and outcomes in infants ≤60 days old with bacteremic urinary tract infection (UTI).
methodsThis multicenter retrospective cohort study included infants ≤60 days old who had concomitant growth of a pathogen in blood and urine cultures at 11 children's hospitals between 2011 and 2016. Short-course parenteral antibiotic duration was defined as ≤7 days, and long-course parenteral antibiotic duration was defined as >7 days. Propensity scores, calculated using patient characteristics, were used to determine the likelihood of receiving long-course parenteral antibiotics. We conducted inverse probability weighting to achieve covariate balance and applied marginal structural models to the weighted population to examine the association between parenteral antibiotic duration and outcomes (30-day UTI recurrence, 30-day all-cause reutilization, and length of stay).
resultsAmong 115 infants with bacteremic UTI, 58 (50%) infants received short-course parenteral antibiotics. Infants who received long-course parenteral antibiotics were more likely to be ill appearing and have growth of a non-
conclusionsYoung infants with bacteremic UTI who received ≤7 days of parenteral antibiotics did not have more frequent recurrent UTIs or hospital reutilization compared with infants who received long-course therapy. Short-course parenteral therapy with early conversion to oral antibiotics may be considered in this population.
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