Evidence map›Paper›PMID 31431458›Full record

ReviewCancer research2019

Wnt Signaling in Cancer: Not a Binary ON:OFF Switch.

Dustin J Flanagan, Elizabeth Vincan, Toby J Phesse

Open access · bronzeAbstract readReview
In one paragraph

Review in Cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Gut microbes · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Wnt signaling and tumors (Review).Molecular and clinical oncology · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Dustin J FlanaganCancer Research UK Beatson Institute, Glasgow, United Kingdom.
Elizabeth VincanUniversity of Melbourne and Victorian Infectious Diseases Reference Laboratory, Doherty Institute of Infection and Immunity, Melbourne, Australia. phesset@cardiff.ac.uk e.vincan@unimelb.edu.au.ORCID https://orcid.org/0000-0002-8607-4849
Toby J PhesseEuropean Cancer Stem Cell Research Institute, Cardiff University, Cardiff, United Kingdom. phesset@cardiff.ac.uk e.vincan@unimelb.edu.au.
Cancer Research UK Scotland Institute · GBCurtin University · AUPeter Doherty Institute · AU

Funding

Medical Research Council MR/R026424/1
6 · The paper itself

Abstract

In the March 1 issue of

Indexed as

Genetic HeterogeneityAntineoplastic AgentsCell MembraneFrizzled ReceptorsHumansIntracellular SpaceNeoplasmsWnt Signaling PathwayAntineoplastic AgentsFrizzled Receptors

Identifiers

PMID31431458
PMCPMC7616966
OpenAlexW2969233593

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.