ArticleAtherosclerosis2019
Functional role of gut microbiota and PCSK9 in the pathogenesis of diabetes mellitus and cardiovascular disease.
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In one paragraph
Article in Atherosclerosis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 33 citations in OpenAlex.
- Daily consumption of Fuzhuan brick tea improves lipid profile and vascular function associated with modulation in gut microbiota composition in healthy adults: a pilot randomized controlled trial.Frontiers in nutrition · 2026Trial
- A six-year longitudinal study identifies a statin-independent association between low LDL-cholesterol and risk of type 2 diabetes.Cardiovascular diabetology · 2025Article
- Comparative LDL-C Lowering Efficacy of Nonstatin Therapies: Inclisiran Is Better Than Ezetimibe, PCSK9 Inhibitors, and Bempedoic Acid.Journal of cardiovascular pharmacology · 2025Article
- Genetics of diabetes and its complications: a comprehensive review.Diabetology & metabolic syndrome · 2025Review
- The differences in intestinal flora and metabolites between H-type hypertension and non-H-type hypertension.Journal of translational medicine · 2025Review
- PCSK9 plasma concentration is associated with epicardial adipose tissue volume and metabolic control in patients with type 1 diabetes.Scientific reports · 2024Observational
- Longitudinal variation of serum PCSK9 in ulcerative colitis: association with disease activity, T helper 1/2/17 cells, and clinical response of tumor necrosis factor inhibitor.Irish journal of medical science · 2024Article
- Sex X Time Interactions in Lp(a) and LDL-C Response to Evolocumab.Biomedicines · 2023Article
- Oral probiotics increased the proportion of Treg, Tfr, and Breg cells to inhibit the inflammatory response and impede gestational diabetes mellitus.Molecular medicine (Cambridge, Mass.) · 2023Article
- Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders.Frontiers in pharmacology · 2023Review
- Article
- Lipid Profile and Atrial Fibrillation: Is There Any Link?Reviews in cardiovascular medicine · 2022Review
- Article
- Article
- Antibody-Based Therapeutics for Atherosclerosis and Cardiovascular Diseases.International journal of molecular sciences · 2021Review
- Inclisiran: a new milestone on the PCSK9 road to tackle cardiovascular risk.European heart journal. Cardiovascular pharmacotherapy · 2021Article
- PCSK9 and the Gut-Liver-Brain Axis: A Novel Therapeutic Target for Immune Regulation in Alcohol Use Disorder.Journal of clinical medicine · 2021Review
- Standardizing translational microbiome studies and metagenomic analyses.Cardiovascular research · 2021Article
- Association of circulating proprotein convertase subtilisin/kexin type 9 levels and the risk of incident type 2 diabetes in subjects with prediabetes: a population-based cohort study.Cardiovascular diabetology · 2020 · on this mapObservational
- The gut microbiota and its interactions with cardiovascular disease.Microbial biotechnology · 2020Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Marco Bruno MorelliDepartment of Medicine, Wilf Family Cardiovascular Research Institute, Einstein-Mount Sinai Diabetes Research Center (ES-DRC), The "Norman Fleischer" Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, New York, NY, USA.
Xujun WangDepartment of Medicine, Wilf Family Cardiovascular Research Institute, Einstein-Mount Sinai Diabetes Research Center (ES-DRC), The "Norman Fleischer" Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, New York, NY, USA; Department of Molecular Pharmacology, Einstein-Mount Sinai Diabetes Research Center (ES-DRC), The "Norman Fleischer" Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, New York, NY, USA.
Gaetano SantulliDepartment of Medicine (Cardiology), Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine - Montefiore University Hospital, New York, NY, USA; Department of Molecular Pharmacology, Einstein-Mount Sinai Diabetes Research Center (ES-DRC), The "Norman Fleischer" Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, New York, NY, USA; Department of Advanced Biomedical Sciences, "Federico II" University, Naples, Italy. Electronic address: gsantulli001@gmail.com.
Albert Einstein College of Medicine · US
Funding
REGULATION OF THE INSULIN RECEPTOR KINASER01DK033823 · NIDDK · UNIVERSITY OF IOWA · PI KURLAND, IRWIN JACK, PESSIN, JEFFREY E. · 1986 to 2022
$6.7MFunctional role of IP3 receptors in the regulation of cardiac myofibroblastsR01HL146691 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SANTULLI, GAETANO · 2019 to 2023
$2.1MBeta Cell Intracellular Calcium and DiabetesR01DK123259 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SANTULLI, GAETANO · 2020 to 2023
$1.7MTargeting intracellular calcium leak as novel therapy for diabetesR00DK107895 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI SANTULLI, GAETANO · 2018 to 2020
$741kNHLBI NIH HHS R01 HL146691NIDDK NIH HHS R00 DK107895NIDDK NIH HHS R01 DK033823NIDDK NIH HHS R01 DK123259
Abstract
PubMed holds no abstract for this paper.
Indexed as
Atrial FibrillationCardiovascular DiseasesDiabetes Mellitus, Type 2EndotoxemiaGastrointestinal MicrobiomeGastrointestinal TractHumansProprotein Convertase 9SubtilisinsPCSK9 protein, humanProprotein Convertase 9SubtilisinsCardiovascular diseaseDiabetes mellitusInflammationMicrobiotaPCSK9
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.