Evidence map›Paper›PMID 31431119›Full record

ReviewBioengineered2019

New insights and rethinking of cinnabar for chemical and its pharmacological dynamics.

Archana Jain, Surendra Sarsaiya, Qin Wu, Jingshan Shi, Yuanfu Lu

RetractedAbstract readHistorical ArticleReviewRetracted Publication
In one paragraph

Review in Bioengineered, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Modulation of the S/HgClNanomaterials (Basel, Switzerland) · 2025
    Article
  4. Cinnabar-induced hormesis inFrontiers in microbiology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Archana JainKey Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University , Guizhou , China.
Surendra SarsaiyaKey Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University , Guizhou , China.ORCID 0000-0002-0850-8592
Qin WuKey Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University , Guizhou , China.
Jingshan ShiKey Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University , Guizhou , China.ORCID 0000-0002-0968-7094
Yuanfu LuKey Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University , Guizhou , China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cinnabar is an attractive mineral with many different uses. It is reported that cinnabar is one of the traditional Chinese's medicines extensively use. The main objective of this critical review is to identify the current overview, concept and chemistry of cinnabar, which includes the process developments, challenges, and diverse options for pharmacology research. It is used as a medicine through probable toxicity, especially when taking overdoes. This review is the first to describe the toxicological effects of cinnabar and its associated compounds. Nuclear magnetic resonance (NMR) dependent metabolomics could be useful for examination of the pharmaceutical consequence. The analysis indicated that the accurate preparation methods, appropriate doses, disease status, ages with drug combinations are significant factors for impacting the cinnabar toxicity. Toxicologically, synthetic mercury sulfide or cinnabar should be notable for mercuric chloride, mercury vapor and methyl mercury for future protection and need several prominent advancements in cinnabar research.

Indexed as

Acute Kidney InjuryAmnesiaAnimalsDrug Dosage CalculationsHistory, AncientHumansHypnotics and SedativesMedicine, AyurvedicMedicine, Chinese TraditionalMercury CompoundsMiceNootropic AgentsPsychomotor AgitationSleep Initiation and Maintenance DisordersToxicity TestscinnabarHypnotics and SedativesMercury CompoundsNootropic AgentsCinnabarmedicinemineral complexpharmacologytoxicology

Identifiers

PMID31431119
PMCPMC6738451

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.