ReviewMolecules (Basel, Switzerland)2019
Review of Alternative Solvents for Green Extraction of Food and Natural Products: Panorama, Principles, Applications and Prospects.
Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
137 citing papers in PubMed.
- Preparation, characterization, and catalytic performance of a 2,3-dihydroxybenzoic acid-based deep eutectic solvent for the synthesis of chromenoquinolinones.RSC advances · 2026Article
- Fructus Sophorae Extract Generated Using the Natural Deep Eutectic Solvent ChCl Urea Activates Wnt/β Catenin and cAMP/MITF Signaling to Stimulate Hair Growth and Pigmentation.International journal of molecular sciences · 2026Article
- Thermochemical Valorization of Silkworm Feeding Waste: Chemical Characterization and Biological Activities of the Pyrolysis-Derived Liquid Fraction.Antioxidants (Basel, Switzerland) · 2026Article
- Agri-Food Wastes as Natural Source of Bioactive Antioxidants: Fourth Edition.Antioxidants (Basel, Switzerland) · 2026Article
- A Review on Ylang-Ylang (Molecules (Basel, Switzerland) · 2026Review
- Novel Caffeine-Assisted Aqueous Extraction Strategy for Enhanced Solubilization of Polycyclic Aromatic Hydrocarbons from Creosote-Treated Waste Wood.Molecules (Basel, Switzerland) · 2026Article
- Cosmeceutical Potential of Matcha (Molecules (Basel, Switzerland) · 2026Article
- Transformation of Agro-Industrial By-Products into High-Value Animal-Derived Foods: Bioactive Compounds, Microbiome-Mediated Biotransformation, Metabolomic Traceability and Circular Valorization.Molecules (Basel, Switzerland) · 2026Review
- From static compromise to dynamic design: a polarity modulation paradigm for multiclass veterinary drug residue analysis in complex foods.Food chemistry: X · 2026Review
- Seasonality: The Driving Force Behind the Antimicrobial and Antioxidant Activities and Biochemical Composition ofMarine drugs · 2026Article
- Improving the yield and biological activity of sage essential oil using NADES: in vitro and in silico insights.Scientific reports · 2026Article
- Selective Extraction of Lipophilic Bioactive Compounds from Industrial Root Meal ofMolecules (Basel, Switzerland) · 2026Article
- Effectiveness of Natural Deep Eutectic Solvents (NADES) in Extracting Bioactive Compounds fromACS omega · 2026Article
- Green Recovery of Bioactive Compounds from Bergamot (Foods (Basel, Switzerland) · 2026Review
- Microwave-Assisted Rapid Extraction of Oleuropein from Olive Leaf By-Product and Processing into Oleuropein@Zeolite Nanohybrids for Antioxidant Food Applications (Fortified Salt and Active Gelatin Films).Molecules (Basel, Switzerland) · 2026Article
- The role of green chemistry in the transformation of agro-industrial wastes for health and environment: a review.Biodegradation · 2026Review
- The role of green chemistry in the transformation of agro-industrial wastes for health and environment: a review.Biodegradation · 2026Review
- Supercritical Fluid Extraction to Valorise Fruit and Vegetable by-Products.Foods (Basel, Switzerland) · 2026Review
- Ultrasound-assisted solvent-free extraction of rosemary absolute oil: A green paradigm for high-efficacy natural antioxidant in frying oil stabilization.Ultrasonics sonochemistry · 2026Article
- Exploring Neuroprotective Potential of Bioactive Compounds Obtained from Artichoke By-Products by Pressurized Liquid Extraction via Response Surface Methodology.International journal of molecular sciences · 2026Article
77 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, almost all extraction processes in the perfume, cosmetic, pharmaceutical, food ingredients, nutraceuticals, biofuel and fine chemical industries rely massively on solvents, the majority of which have petroleum origins. The intricate processing steps involved in the industrial extraction cycle makes it increasingly difficult to predict the overall environmental impact; despite the tremendous energy consumption and the substantial usage of solvents, often the yields are indicated in decimals. The ideal alternative solvents suitable for green extraction should have high solvency, high flash points with low toxicity and low environmental impacts, be easily biodegradable, obtained from renewable (non-petrochemical) resources at a reasonable price and should be easy to recycle without any deleterious effect to the environment. Finding the perfect solvent that meets all the aforementioned requirements is a challenging task, thus the decision for the optimum solvent will always be a compromise depending on the process, the plant and the target molecules. The objective of this comprehensive review is to furnish a vivid picture of current knowledge on alternative, green solvents used in laboratories and industries alike for the extraction of natural products focusing on original methods, innovation, protocols, and development of safe products.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.