Evidence map›Paper›PMID 31430968›Full record

ArticleBiomolecules2019

The Protective Effect of Hispidin against Hydrogen Peroxide-Induced Oxidative Stress in ARPE-19 Cells via Nrf2 Signaling Pathway.

Sung-Ying Huang, Shu-Fang Chang, Siu-Fung Chau, Sheng-Chun Chiu

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 44 citations in OpenAlex.

  1. A Fungal-Derived Bioactive Resource for Cochlear Protection:Journal of microbiology and biotechnology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Green Extraction and Liposomal Encapsulation ofMolecules (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Food science of animal resources · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Therapeutic Potential of Hispidin-Fungal and Plant Polyketide.Journal of fungi (Basel, Switzerland) · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Sung-Ying HuangDepartment of Ophthalmology, Hsinchu Mackay Memorial Hospital, Hsinchu 30071, Taiwan.
Shu-Fang ChangDepartment of Research, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 42743, Taiwan.
Siu-Fung ChauDepartment of Ophthalmology, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 42743, Taiwan. Cipechau@gmail.com.
Sheng-Chun ChiuDepartment of Research, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 42743, Taiwan. Honeyhopes@gmail.com.
Taipei Tzu Chi Hospital · TWMackay Memorial Hospital · TWTzu Chi University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hispidin, a polyphenol compound isolated from

Indexed as

AdultCell LineCell SurvivalDose-Response Relationship, DrugHumansHydrogen PeroxideNF-E2-Related Factor 2Oxidative StressProtective AgentsPyronesRetinal Pigment EpitheliumSignal TransductionStructure-Activity RelationshiphispidinHydrogen PeroxideNFE2L2 protein, humanNF-E2-Related Factor 2Protective AgentsPyronesage-related macular degenerationARPE-19hispidinhydrogen peroxideNrf2oxidative stress

Identifiers

PMID31430968
PMCPMC6724002
OpenAlexW2969365600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.