Evidence map›Paper›PMID 31430908›Full record

ArticleMolecules (Basel, Switzerland)2019

In Vitro Inhibitory Effects of APINACA on Human Major Cytochrome P450, UDP-Glucuronosyltransferase Enzymes, and Drug Transporters.

Sunjoo Kim, Won-Gu Choi, Mihwa Kwon, Sowon Lee, Yong-Yeon Cho, Joo Young Lee, Han Chang Kang, Im-Sook Song, Hye Suk Lee

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Synthetic Cannabinoid-Related Deaths in England, 2012-2019.Cannabis and cannabinoid research · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sunjoo KimBK21 PLUS Team for Creative Leader Program for Pharmacomics-Based Future Pharmacy, College of Pharmacy, The Catholic University of Korea, Bucheon 14662, Korea.ORCID 0000-0001-7679-0270
Won-Gu ChoiBK21 PLUS Team for Creative Leader Program for Pharmacomics-Based Future Pharmacy, College of Pharmacy, The Catholic University of Korea, Bucheon 14662, Korea.
Mihwa KwonCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Korea.
Sowon LeeCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Korea.
Yong-Yeon ChoBK21 PLUS Team for Creative Leader Program for Pharmacomics-Based Future Pharmacy, College of Pharmacy, The Catholic University of Korea, Bucheon 14662, Korea.
Joo Young LeeBK21 PLUS Team for Creative Leader Program for Pharmacomics-Based Future Pharmacy, College of Pharmacy, The Catholic University of Korea, Bucheon 14662, Korea.
Han Chang KangBK21 PLUS Team for Creative Leader Program for Pharmacomics-Based Future Pharmacy, College of Pharmacy, The Catholic University of Korea, Bucheon 14662, Korea.ORCID 0000-0003-0696-1155
Im-Sook SongCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Korea. songimsook1@gmail.com.
Hye Suk LeeBK21 PLUS Team for Creative Leader Program for Pharmacomics-Based Future Pharmacy, College of Pharmacy, The Catholic University of Korea, Bucheon 14662, Korea. sianalee@catholic.ac.kr.ORCID 0000-0003-1055-9628
Catholic University of Korea · KRKyungpook National University · KR

Funding

National Research Foundation of Korea NRF-2015M3A9E1028325, NRF-2017M3A9F5028608, and NRF-2017R1A4A1015036
6 · The paper itself

Abstract

APINACA (known as AKB48,

Indexed as

Biological TransportCannabinoidsCell LineCytochrome P-450 Enzyme InhibitorsCytochrome P-450 Enzyme SystemDrug InteractionsGlucuronosyltransferaseHEK293 CellsHumansMembrane Transport ProteinsMicrosomes, LiverOrganic Anion TransportersCannabinoidsCytochrome P-450 Enzyme InhibitorsCytochrome P-450 Enzyme SystemGlucuronosyltransferaseMembrane Transport ProteinsOrganic Anion TransportersAPINACAcytochrome P450drug–drug interactiondrug transportersuridine 5′-diphospho-glucuronosyltransferases

Identifiers

PMID31430908
PMCPMC6720883
OpenAlexW2968067900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.