Evidence map›Paper›PMID 31430434›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Differential long-term regulation of TAS2R14 by structurally distinct agonists.

Jung A Woo, Maria Castaño, Ashley Goss, Donghwa Kim, Eric M Lewandowski, Yu Chen, Stephen B Liggett

Open access · greenAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. A Par3/LIM Kinase/Cofilin Pathway Mediates Human Airway Smooth Muscle Relaxation by TAS2R14.American journal of respiratory cell and molecular biology · 2023
    Article
  6. Pharmacology of T2R Mediated Host-Microbe Interactions.Handbook of experimental pharmacology · 2022
    Article
  7. Identification and characterization of an atypical Gαs-biased βProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jung A WooDepartment of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
Maria CastañoDepartment of Medicine, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
Ashley GossDepartment of Medicine, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
Donghwa KimDepartment of Medicine, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
Eric M LewandowskiDepartment of Molecular Medicine, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
Yu ChenDepartment of Molecular Medicine, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
Stephen B LiggettDepartment of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
University of South Florida · US

Funding

Project 4 - OGR1- and TSPO- dependent mechanisms mediated by benzodiazepines affecting ASM contractionP01HL114471 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI LIGGETT, STEPHEN B · 2013 to 2023
$23.9M
Molecular properties of B-adrenergic receptors in AsthmaR37HL045967 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI LIGGETT, STEPHEN B · 2002 to 2012
$3.2M
MOLECULAR PROPERTIES OF B-ADRENERGIC RECEPTORS IN ASTHMAR01HL045967 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI LIGGETT, STEPHEN B · 1990 to 2018
$1.3M
Molecular properties of B-adrenergic receptors in AsthmaR56HL045967 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI LIGGETT, STEPHEN B · 2015 to 2015
$374k
NHLBI NIH HHS P01 HL114471NHLBI NIH HHS R01 HL045967NHLBI NIH HHS R37 HL045967NHLBI NIH HHS R56 HL045967
6 · The paper itself

Abstract

Bitter taste receptor-14 (TAS2R14) is a GPCR also expressed on human airway smooth muscle cells, which signals to intracellular [Ca

Indexed as

beta-ArrestinsCalciumDiphenhydramineEndosomesHEK293 CellsHumansMolecular Docking SimulationReceptors, G-Protein-CoupledTaste Receptors, Type 2beta-ArrestinsCalciumDiphenhydramineReceptors, G-Protein-CoupledTaste Receptors, Type 2[Ca2+]idesensitizationdown-regulationinternalizationβ-arrestin

Identifiers

PMID31430434
PMCPMC6902689
OpenAlexW2969482246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.