ArticlePLoS neglected tropical diseases2019
Detection of classic and cryptic Strongyloides genotypes by deep amplicon sequencing: A preliminary survey of dog and human specimens collected from remote Australian communities.
Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- A systematic review and meta-analysis of human and zoonotic dog soil-transmitted helminth infections in Australian Indigenous communities.PLoS neglected tropical diseases · 2022Pooled it
- From the feces to the genome: a guideline for the isolation and preservation of Strongyloides stercoralis in the field for genetic and genomic analysis of individual worms.Parasites & vectors · 2019Guideline
- Environmental contamination with canine soil-transmitted helminths in New Zealand urban areas: A nationwide molecular, spatial, and risk factor analysis survey.One health (Amsterdam, Netherlands) · 2026Article
- Strongyloides Genetic Diversity among Humans, Dogs, and Nonhuman Primates, Central African Republic, 2016-2022.Emerging infectious diseases · 2026Article
- The potential threat of Strongyloides spp. to mountain gorillas and public health in Bwindi Impenetrable National Park, Uganda.Parasitology research · 2026Article
- Retrospective screening reveals the rare occurrence of zoonoticParasitology · 2026Article
- Taxonomy ofParasitology · 2026Review
- Molecular taxonomic characterisation ofFrontiers in parasitology · 2026Article
- Molecular taxonomic study ofFrontiers in parasitology · 2026Article
- Zoonotic Risk of Intestinal Parasites in Ghana's Protected Areas: A Nexus for Human-Nonhuman Primates-Dog Interactions.Journal of parasitology research · 2026Article
- Notes on the threadwormInternational journal for parasitology. Parasites and wildlife · 2025Article
- Human, canine and feline strongyloidiasis: beyondParasitology · 2025Review
- A population genetic analysis of the nematodeProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Cutaneous Larva Migrans Refractory to Therapy with Ivermectin: Case Report and Review of Implicated Zoonotic Pathogens, Epidemiology, Anthelmintic Drug Resistance and Therapy.Tropical medicine and infectious disease · 2025Article
- ChronicJournal of medical microbiology · 2024Article
- Genomic analysis of Strongyloides stercoralis and Strongyloides fuelleborni in Bangladesh.PLoS neglected tropical diseases · 2024Article
- A Pilot Study for the Characterization ofMicroorganisms · 2024Article
- High-throughput sequencing ofParasitology · 2024Article
- Strongyloides stercoralis genotyping in a human population in southwestern Iran.Parasites & vectors · 2024Article
- AdvancingPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Strongyloidiasis is caused by the human infective nematodes Strongyloides stercoralis, Strongyloides fuelleborni subsp. fuelleborni and Strongyloides fuelleborni subsp. kellyi. The zoonotic potential of S. stercoralis and the potential role of dogs in the maintenance of strongyloidiasis transmission has been a topic of interest and discussion for many years. In Australia, strongyloidiasis is prevalent in remote socioeconomically disadvantaged communities in the north of the continent. Being an isolated continent that has been separated from other regions for a long geological period, description of diversity of Australian Strongyloides genotypes adds to our understanding of the genetic diversity within the genus. Using PCR and amplicon sequencing (Illumina sequencing technology), we sequenced the Strongyloides SSU rDNA hyper-variable I and hyper-variable IV regions using Strongyloides-specific primers, and a fragment of the mtDNA cox1 gene using primers that are broadly specific for Strongyloides sp. and hookworms. These loci were amplified from DNA extracted from Australian human and dog faeces, and one human sputum sample. Using this approach, we confirm for the first time that potentially zoonotic S. stercoralis populations are present in Australia, suggesting that dogs represent a potential reservoir of human strongyloidiasis in remote Australian communities.
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Registered trials
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