Evidence map›Paper›PMID 31429286›Full record

ArticleBiochemistry2019

BPEI-Induced Delocalization of PBP4 Potentiates β-Lactams against MRSA.

Melissa A Hill, Anh K Lam, Patricia Reed, Madeline C Harney, Beatrice A Wilson, Erika L Moen, Summer N Wright, Mariana G Pinho, Charles V Rice

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
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  4. NeutralizingACS omega · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Melissa A HillDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center , University of Oklahoma , 101 Stephenson Parkway , Norman , Oklahoma 73019 , United States.
Anh K LamDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center , University of Oklahoma , 101 Stephenson Parkway , Norman , Oklahoma 73019 , United States.
Patricia ReedLaboratory of Bacterial Cell Biology, Instituto de Tecnologia Química e Biologica António Xavier , Universidade NOVA de Lisboa , Av. da República , 2780-157 Oeiras , Portugal.
Madeline C HarneyDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center , University of Oklahoma , 101 Stephenson Parkway , Norman , Oklahoma 73019 , United States.
Beatrice A WilsonDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center , University of Oklahoma , 101 Stephenson Parkway , Norman , Oklahoma 73019 , United States.
Erika L MoenDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center , University of Oklahoma , 101 Stephenson Parkway , Norman , Oklahoma 73019 , United States.
Summer N WrightDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center , University of Oklahoma , 101 Stephenson Parkway , Norman , Oklahoma 73019 , United States.
Mariana G PinhoLaboratory of Bacterial Cell Biology, Instituto de Tecnologia Química e Biologica António Xavier , Universidade NOVA de Lisboa , Av. da República , 2780-157 Oeiras , Portugal.
Charles V RiceDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center , University of Oklahoma , 101 Stephenson Parkway , Norman , Oklahoma 73019 , United States.ORCID 0000-0003-1424-405X
University of Oklahoma · USUniversidade Nova de Lisboa · PT

Funding

Antibiotic Potentiators Targeting Biofilms of MRSA and MRSER03AI142420 · NIAID · UNIVERSITY OF OKLAHOMA · PI RICE, CHARLES V · 2019 to 2020
$142k
NIAID NIH HHS R03 AI142420
6 · The paper itself

Abstract

With its high morbidity rate and increasing resistance to treatment, methicillin-resistant

Indexed as

Anti-Bacterial Agentsbeta-Lactam ResistanceCell DivisionDrug SynergismMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsPenicillin-Binding ProteinsPenicillinsPolyethyleneimineTeichoic AcidsAnti-Bacterial AgentsPenicillin-Binding ProteinsPenicillinsPolyethyleneimineTeichoic Acids

Identifiers

PMID31429286
PMCPMC6941424
OpenAlexW2969837724

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.