Evidence map›Paper›PMID 31429198›Full record

Trial reportArthritis & rheumatology (Hoboken, N.J.)2020

Five-Year Outcome of Operative and Nonoperative Management of Meniscal Tear in Persons Older Than Forty-Five Years.

Jeffrey N Katz, Swastina Shrestha, Elena Losina, Morgan H Jones, Robert G Marx, Lisa A Mandl, Bruce A Levy, Lindsey A MacFarlane, Kurt P Spindler, Genevieve S Silva and 2 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Arthritis & rheumatology (Hoboken, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00597012 (Partial Meniscectomy Versus Nonoperative Management in Meniscal Tear With OA), which is not on this map. Cited by 36 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 5 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00597012 nacompletednot on this map

Partial Meniscectomy Versus Nonoperative Management in Meniscal Tear With OA: A Randomized Controlled Trial (MeTeOR)

TypeinterventionalSponsorBrigham and Women's HospitalRan2008 to 2025Enrolled351ConditionsOsteoarthritisArmsArthroscopic partial menisectomy, Standard physical therapy, Postoperative rehabilitative physical therapy
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 5 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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  17. Costs and Timing of Surgery in the Management of Meniscal Tears.Orthopaedic journal of sports medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Jeffrey N KatzBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0003-2104-4670
Swastina ShresthaBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Elena LosinaBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-3424-0892
Morgan H JonesCleveland Clinic, Cleveland, Ohio.
Robert G MarxHospital for Special Surgery, Weill Cornell Medicine, New York, New York.
Lisa A MandlHospital for Special Surgery, Weill Cornell Medicine, New York, New York.
Bruce A LevyMayo Clinic, Rochester, Minnesota.
Lindsey A MacFarlaneBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0001-8398-3804
Kurt P SpindlerCleveland Clinic, Cleveland, Ohio.
Genevieve S SilvaBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
METEOR Investigators
Jamie E CollinsBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0001-8413-007X
Brigham and Women's Hospital · USCleveland Clinic · USHospital for Special Surgery · USMayo Clinic · US

Funding

PARTIAL MENISCECTOMY VS. NONOPERATIVE MGMT. IN MENISCAL TEAR WITH OA: AN RCTR01AR055557 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI KATZ, JEFFREY NEIL · 2007 to 2023
$11.2M
VERITY: Value and Evidence in Rheumatology using bioInformaTics, and advanced analYticsP30AR072577 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Daniel Hal Solomon · 2017 to 2026
$9.8M
Patient Oriented Research and Mentoring Program in OrthopedicsK24AR057827 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI LOSINA, ELENA · 2010 to 2019
$1.7M
Meniscus status and activity level after ACLK23AR066133 · NIAMS · CLEVELAND CLINIC LERNER COM-CWRU · PI JONES, MORGAN HERANCOURT · 2015 to 2019
$745k
NIAMS NIH HHS K23 AR066133NIAMS NIH HHS K24 AR057827NIAMS NIH HHS P30 AR072577NIAMS NIH HHS R01 AR055557NIH HHS K24 AR057827Rheumatology Research Foundation
6 · The paper itself

Abstract

objectiveTo determine the 5-year outcome of treatment for meniscal tear in osteoarthritis.

methodsWe examined 5-year follow-up data from the Meniscal Tear in Osteoarthritis Research trial (METEOR) of physical therapy versus arthroscopic partial meniscectomy. We performed primary intent-to-treat (ITT) and secondary as-treated analyses. The primary outcome measure was the Knee Injury and Osteoarthritis Outcome Score (KOOS) pain scale; total knee replacement (TKR) was a secondary outcome measure. We used piecewise linear mixed models to describe change in KOOS pain. We calculated 5-year cumulative TKR incidence and used a Cox model to estimate hazard ratios (HRs) for TKR, with 95% confidence intervals (95% CIs).

resultsThree hundred fifty-one participants were randomized. In the ITT analysis, the KOOS pain scores were ~46 (scale of 0 [no pain] to 100 [most pain]) at baseline in both groups. Pain scores improved substantially in both groups over the first 3 months, continued to improve through the next 24 months (to ~18 in each group), and were stable at 24-60 months. Results of the as-treated analyses of the KOOS pain score were similar. Twenty-five participants (7.1% [95% CI 4.4-9.8%]) underwent TKR over 5 years. In the ITT model, the HR for TKR was 2.0 (95% CI 0.8-4.9) for subjects randomized to the arthroscopic partial meniscectomy group, compared to those randomized to the physical therapy group. In the as-treated analysis, the HR for TKR was 4.9 (95% CI 1.1-20.9) for subjects ultimately treated with arthroscopic partial meniscectomy, compared to those treated nonoperatively.

conclusionPain improved considerably in both groups over 60 months. While ITT analysis revealed no statistically significant differences following TKR, greater frequency of TKR in those undergoing arthroscopic partial meniscectomy merits further study.

Indexed as

AgedAge FactorsFemaleFollow-Up StudiesHumansIntention to Treat AnalysisMaleMiddle AgedOsteoarthritis, KneeTibial Meniscus InjuriesTime FactorsTreatment Outcome

Identifiers

PMID31429198
PMCPMC6994332
OpenAlexW2969651328

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.