Evidence map›Paper›PMID 31429086›Full record

ArticleImmunology2019

Adipokines and the control of mast cell functions: from obesity to inflammation?

Simon Milling

Open access · bronzeAbstract readEditorialComment
In one paragraph

Article in Immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Prohibitions in the meta-inflammatory response: a review.Frontiers in molecular biosciences · 2024
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Leptin ElicitsFrontiers in endocrinology · 2020
    Article
  12. Article
  13. Article
  14. Adipocytes, mast cells and angiogenesis.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Simon MillingInstitute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.ORCID 0000-0003-4384-5516
University of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipokines are peptide mediators produced by fat cells in adipose tissue that exert a powerful influence on many body systems, including the immune system. Leptin and adiponectin are among the best known of these molecules and have been shown to affect the functions of, for instance, dendritic cells, neutrophils, and innate lymphoid cells. Here we present the results of a new study that describes the effects of leptin and adiponectin on mast cells, a cell type which plays an important role in controlling inflammatory responses. This provides an improved understanding of how obesity may contribute to chronic inflammation, and lead to a wide range of inflammatory pathologies.

Indexed as

AdiponectinLeptinAdipokinesAdipose TissueHumansImmunity, InnateInflammationLymphocytesMast CellsObesityAdipokinesAdiponectinLeptin

Identifiers

PMID31429086
PMCPMC6700462
OpenAlexW2969968098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.