Evidence map›Paper›PMID 31428990›Full record

ArticleJournal of neurovirology2020

Peripheral polyneuropathy associated with Chikungunya virus infection.

Vanessa P Silva, Dacylla S Costa, Vania C C V L Carvalho, Tereza C C S Garcês, Emanuela L T Barros, Jefferson S Oliveira, Anna C T C Pereira, Gustavo P Ferreira

Abstract readCase Reports
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In one paragraph

Article in Journal of neurovirology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Vanessa P SilvaLaboratory of Biochemistry and Molecular Biology of Microorganisms and Plants, Federal University of Piauí, Campus Ministro Reis Velloso-CMRV, Parnaíba, Brazil.
Dacylla S CostaLaboratory of Biochemistry and Molecular Biology of Microorganisms and Plants, Federal University of Piauí, Campus Ministro Reis Velloso-CMRV, Parnaíba, Brazil.
Vania C C V L CarvalhoDepartment of Medicine, Federal University of Piauí, Campus Ministro Reis Velloso-CMRV, Parnaíba, Brazil.
Tereza C C S GarcêsDepartment of Medicine, Faculty of Human Sciences, Exact and Health of Piauí, Parnaíba, Brazil.
Emanuela L T BarrosLaboratory of Biochemistry and Molecular Biology of Microorganisms and Plants, Federal University of Piauí, Campus Ministro Reis Velloso-CMRV, Parnaíba, Brazil.
Jefferson S OliveiraLaboratory of Biochemistry and Molecular Biology of Microorganisms and Plants, Federal University of Piauí, Campus Ministro Reis Velloso-CMRV, Parnaíba, Brazil.
Anna C T C PereiraLaboratory of Biochemistry and Molecular Biology of Microorganisms and Plants, Federal University of Piauí, Campus Ministro Reis Velloso-CMRV, Parnaíba, Brazil.
Gustavo P FerreiraLaboratory of Biochemistry and Molecular Biology of Microorganisms and Plants, Federal University of Piauí, Campus Ministro Reis Velloso-CMRV, Parnaíba, Brazil. gtvpf@ufpi.edu.br.ORCID 0000-0002-8113-905X
Universidade Federal do Piauí · BRUniversidade Estadual do Piauí · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Chikungunya virus (CHIKV) is an arbovirus transmitted to humans through mosquito bites and can cause a series of symptoms ranging from a benign febrile illness to severe neurological conditions. We report the identification of CHIKV in a serum sample from an elderly woman with febrile illness and severe arthralgia in Brazil. The occurrence was found of peripheral polyneuropathy affecting the upper and lower limbs evidenced by electroneuromyographic findings. The patient was treated with a corticoid associated with methotrexate, suggesting that the pathophysiological basis of the case in question may be related to an immune-mediated response by T cells and inflammatory cytokines. This finding reinforces the need to be aware of the emergence of neuroinfections related to CHIKV and effective diagnoses for the early detection of neurological alterations, favoring the clinical management of these patients.

Indexed as

AgedBrazilChikungunya FeverFemaleHumansImmunosuppressive AgentsMethotrexatePolyneuropathiesImmunosuppressive AgentsMethotrexateArthralgiaChikungunyaPolyneuropathy

Identifiers

PMID31428990
OpenAlexW2969469571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.