Evidence map›Paper›PMID 31428925›Full record

ReviewVirus genes2019

Inventory of molecular markers affecting biological characteristics of avian influenza A viruses.

Annika Suttie, Yi-Mo Deng, Andrew R Greenhill, Philippe Dussart, Paul F Horwood, Erik A Karlsson

Open access · hybridAbstract readReview
In one paragraph

Review in Virus genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 174 papers.

0numbers the graph read from it
0cells of the map it votes in
174citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

174 citing papers in PubMed, 208 citations in OpenAlex.

  1. Article
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  5. Avian influenza overview June-August 2026.EFSA journal. European Food Safety Authority · 2026
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  11. Avian influenza overview March-May 2026.EFSA journal. European Food Safety Authority · 2026
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  20. Imported case of avian influenza A(H9N2) virus infection in a patient with miliary tuberculosis, Italy, March 2026.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article

114 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Annika SuttieVirology Unit, Institut Pasteur du Cambodge, Institut Pasteur International Network, 5 Monivong Blvd, PO Box #983, Phnom Penh, Cambodia.
Yi-Mo DengWorld Health Organization Collaborating Centre for Reference and Research on Influenza, Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.
Andrew R GreenhillSchool of Health and Life Sciences, Federation University, Churchill, Australia.
Philippe DussartVirology Unit, Institut Pasteur du Cambodge, Institut Pasteur International Network, 5 Monivong Blvd, PO Box #983, Phnom Penh, Cambodia.
Paul F HorwoodCollege of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD, Australia.
Erik A KarlssonVirology Unit, Institut Pasteur du Cambodge, Institut Pasteur International Network, 5 Monivong Blvd, PO Box #983, Phnom Penh, Cambodia. ekarlsson@pasteur-kh.org.ORCID http://orcid.org/0000-0001-6004-5671
Federation University · AUInstitut Pasteur du Cambodge · KHJames Cook University · AUPeter Doherty Institute · AU

Funding

U.S. Department of Health and Human Services IDSEP140020-01-00
6 · The paper itself

Abstract

Avian influenza viruses (AIVs) circulate globally, spilling over into domestic poultry and causing zoonotic infections in humans. Fortunately, AIVs are not yet capable of causing sustained human-to-human infection; however, AIVs are still a high risk as future pandemic strains, especially if they acquire further mutations that facilitate human infection and/or increase pathogenesis. Molecular characterization of sequencing data for known genetic markers associated with AIV adaptation, transmission, and antiviral resistance allows for fast, efficient assessment of AIV risk. Here we summarize and update the current knowledge on experimentally verified molecular markers involved in AIV pathogenicity, receptor binding, replicative capacity, and transmission in both poultry and mammals with a broad focus to include data available on other AIV subtypes outside of A/H5N1 and A/H7N9.

Indexed as

AnimalsBirdsDrug Resistance, ViralGenetic MarkersHumansInfluenza A Virus, H5N1 SubtypeInfluenza A Virus, H7N9 SubtypeInfluenza, HumanInfluenza in BirdsPandemicsPoultryZoonosesGenetic MarkersAvian influenzaInfluenza virusMolecular inventoryMolecular markerMutationRisk assessment

Identifiers

PMID31428925
PMCPMC6831541
OpenAlexW2969265469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.