Evidence map›Paper›PMID 31428834›Full record

ArticleWorld journal of surgery2019

Largely Unchanged Annual Incidence and Overall Survival of Pleural Mesothelioma in the USA.

Hari B Keshava, Andrew Tang, Hafiz Umair Siddiqui, Siva Raja, Daniel P Raymond, Alejandro Bribriesco, James Stevenson, Sudish C Murthy, Usman Ahmad

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in World journal of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Malignant pleural disease.Breathe (Sheffield, England) · 2023
    Review
  4. Review
  5. High Expression ofBioMed research international · 2023
    Article
  6. Review
  7. Mesothelioma Risk Score: A New Prognostic Pretreatment, Clinical-Molecular Algorithm for Malignant Pleural Mesothelioma.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2021
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hari B KeshavaDepartment of Thoracic and Cardiovascular Surgery, Taussig Cancer Center, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue / Mail Stop J4-1, Cleveland, OH, 44195, USA.
Andrew TangDepartment of Thoracic and Cardiovascular Surgery, Taussig Cancer Center, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue / Mail Stop J4-1, Cleveland, OH, 44195, USA.
Hafiz Umair SiddiquiDepartment of Thoracic and Cardiovascular Surgery, Taussig Cancer Center, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue / Mail Stop J4-1, Cleveland, OH, 44195, USA.
Siva RajaDepartment of Thoracic and Cardiovascular Surgery, Taussig Cancer Center, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue / Mail Stop J4-1, Cleveland, OH, 44195, USA.
Daniel P RaymondDepartment of Thoracic and Cardiovascular Surgery, Taussig Cancer Center, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue / Mail Stop J4-1, Cleveland, OH, 44195, USA.
Alejandro BribriescoDepartment of Thoracic and Cardiovascular Surgery, Taussig Cancer Center, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue / Mail Stop J4-1, Cleveland, OH, 44195, USA.
James StevensonDepartment of Thoracic and Cardiovascular Surgery, Taussig Cancer Center, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue / Mail Stop J4-1, Cleveland, OH, 44195, USA.
Sudish C MurthyDepartment of Thoracic and Cardiovascular Surgery, Taussig Cancer Center, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue / Mail Stop J4-1, Cleveland, OH, 44195, USA.
Usman AhmadDepartment of Thoracic and Cardiovascular Surgery, Taussig Cancer Center, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue / Mail Stop J4-1, Cleveland, OH, 44195, USA. ahmadu@ccf.org.
Cleveland Clinic · US

Funding

Cleveland Clinic Cardiothoracic Collaborative Clinical Center - C6U01HL088955 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI BLACKSTONE, EUGENE HUBERT · 2007 to 2013
$2.5M
NHLBI NIH HHS U01 HL088955
6 · The paper itself

Abstract

backgroundProjections based on regulations curtailing asbestos use in the USA suggest that peak incidence of pleural mesothelioma would occur between 2000 and 2005 and then decline. We analyzed the National Cancer Database (NCDB) to assess current trends in disease incidence, patient demographics, cancer treatment, and survival.

methodsThe NCDB was queried to identify patients diagnosed with pleural mesothelioma from 2004 through 2014. Clinical and pathologic characteristics, treatments, and survival were analyzed. Risk factors for death were identified by multivariable Cox regression.

resultsA total of 20,988 patients with pleural mesothelioma were reported to the NCDB. The number of cases per year increased from 1783 to 1961, accounting for roughly 0.3% of all reported cancers each year. The proportion of elderly patients increased from 75 to 80%, but distribution by sex remained constant (20% female). The proportion of patients undergoing treatment increased from 34 to 54%. One-year survival increased from 37 to 47% and 3-year survival from 9 to 15% (p < 0.001). Factors associated with improved survival included younger age, female sex, epithelioid histology, treatment in an academic center, health insurance, higher income, and multimodality therapy.

conclusionsThe annual incidence of mesothelioma has not declined this century and remains stable. Reporting of histologic and clinical staging has improved. National trends suggest that survival is slowly increasing despite an aging cohort. Multimodal therapy and treatment at academic centers are modifiable risk factors associated with improved survival.

Indexed as

AdolescentAdultAgedAged, 80 and overFemaleHumansIncidenceLung NeoplasmsMaleMesotheliomaMesothelioma, MalignantMiddle AgedPleural NeoplasmsUnited StatesYoung Adult

Identifiers

PMID31428834
OpenAlexW2969746975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.