Evidence map›Paper›PMID 31428699›Full record

ArticleCommunications biology2019

Hemoglobin S and C affect biomechanical membrane properties of

Benjamin Fröhlich, Julia Jäger, Christine Lansche, Cecilia P Sanchez, Marek Cyrklaff, Bernd Buchholz, Serge Theophile Soubeiga, Jacque Simpore, Hiroaki Ito, Ulrich S Schwarz and 2 more

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Contact Dynamics of CytoadheringACS infectious diseases · 2025
    Article
  3. Article
  4. Biophysical Tools and Concepts Enable Understanding of Asexual Blood Stage Malaria.Frontiers in cellular and infection microbiology · 2022
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Benjamin Fröhlich1Physical Chemistry of Biosystems, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany.
Julia Jäger2Institute for Theoretical Physics and BioQuant-Center for Quantitative Biology, Philosophenweg 19, Heidelberg University, 69120 Heidelberg, Germany.
Christine Lansche3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Cecilia P Sanchez3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Marek Cyrklaff3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Bernd Buchholz4Department of Hematology and Oncology, University Children's Hospital, Medical Faculty Mannheim, 68167 Mannheim, Germany.
Serge Theophile Soubeiga5Biomolecular ResearchCenter Pietro Annigoni, University of Ouagadougou, 01 BP 364 Ouagadougou, Burkina Faso.
Jacque Simpore5Biomolecular ResearchCenter Pietro Annigoni, University of Ouagadougou, 01 BP 364 Ouagadougou, Burkina Faso.
Hiroaki Ito6Department of Mechanical Engineering, Osaka University, Suita, Osaka 565-0871 Japan.
Ulrich S Schwarz2Institute for Theoretical Physics and BioQuant-Center for Quantitative Biology, Philosophenweg 19, Heidelberg University, 69120 Heidelberg, Germany.ORCID 0000-0003-1483-640X
Michael Lanzer3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.ORCID 0000-0002-0220-6526
Motomu Tanaka1Physical Chemistry of Biosystems, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany.ORCID 0000-0003-3663-9554
Heidelberg University · DEUniversité Joseph Ki-Zerbo · BFKyoto University · JPOsaka Gakuin University · JPUniversity of Mannheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During intraerythrocytic development, the human malaria parasite

Indexed as

Biomechanical PhenomenaComputer SimulationErythrocyte MembraneHemoglobin CHemoglobin, SickleHumansMutationNumerical Analysis, Computer-AssistedPlasmodium falciparumHemoglobin CHemoglobin, SickleMembrane biophysicsParasitic infection

Identifiers

PMID31428699
PMCPMC6692299
OpenAlexW2968576840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.