Evidence map›Paper›PMID 31428643›Full record

ArticleBioMed research international2019

Vimentin Overexpressions Induced by Cell Hypoxia Promote Vasculogenic Mimicry by Renal Cell Carcinoma Cells.

Hao Lin, Yingkai Hong, Bin Huang, Xincheng Liu, Junhong Zheng, Shaopeng Qiu

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Curcumin Inhibits Vasculogenic MimicryCurrent cancer drug targets · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hao LinDepartment of Urology, The Second Affiliated Hospital of Shantou University Medical College, China.ORCID https://orcid.org/0000-0002-1005-4585
Yingkai HongDepartment of Urology, The First Affiliated Hospital of Shantou University Medical College, China.
Bin HuangDepartment of Urology, The First Affiliated Hospital, Sun Yat-sen University, China.
Xincheng LiuDepartment of Urology, The Second Affiliated Hospital of Shantou University Medical College, China.
Junhong ZhengDepartment of Urology, The Second Affiliated Hospital of Shantou University Medical College, China.
Shaopeng QiuDepartment of Urology, The First Affiliated Hospital of Shantou University Medical College, China.
Shantou University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vasculogenic mimicry (VM), the novel approach for tumor cells to obtain blood supply, was reported to be involved in antiangiogenic resistance and poor prognosis in renal cell carcinoma (RCC). However, the molecular mechanisms underlying VM formed by RCC cells are still not clearly depicted. In the present study, we found that OS-RC-2 acquired the VM forming ability accompanied with the increased expressions of Vimentin and AXL and decreased expression of E-Cadherin by CoCl

Indexed as

Gene Expression Regulation, NeoplasticAdultAgedAged, 80 and overCarcinoma, Renal CellCell HypoxiaCell Line, TumorCell MovementCobaltFemaleGene Knockdown TechniquesHumansKidney NeoplasmsMaleMiddle AgedNeoplasm InvasivenessCobaltcobaltous chlorideNeoplasm ProteinsVimentinVIM protein, human

Identifiers

PMID31428643
PMCPMC6679895
OpenAlexW2962976847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.