ArticleFrontiers in oncology2019
Intracranial Squamous Cell Carcinoma Arising From a Cerebellopontine Angle Epidermoid Cyst Remnant Four Decades After Partial Resection.
Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Epidermoid cysts of the cerebellopontine angle in pediatric population-an institutional surgical case series and review of literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Pooled it
- Role of stereotactic radiosurgery for intracranial epidermoid tumors: a systematic review to assess its safety, efficacy, and complication profile.Journal of neuro-oncology · 2025Pooled it
- Long-term follow up of malignant transformation of epidermoid cyst at the cerebellopontine angle based on serial imaging findings; A case report and literature review.International cancer conference journal · 2026Article
- Article
- Primary intracranial adenocarcinoma associated with an epidermoid cyst: a case report and literature review.Frontiers in oncology · 2026Article
- Long-term quality of life after surgery for cerebellopontine angle epidermoid cysts: a cross-sectional study.Brain & spine · 2026Article
- Malignant Transformation of a Brain Neurenteric Cyst: A Case Report.Iranian journal of pathology · 2026Article
- Article
- Whole Exome Sequencing of Intracranial Epidermoid Cysts Reveals Immune-Associated Mechanistic and Potential Targets.Cancers · 2024Article
- Epidermoid cyst in atypical intracranial areas transformed to epidermoid carcinoma: a case report.The Journal of international medical research · 2023Article
- Concurrent occurrence of squamous cell carcinoma in a cerebellopontine angle epidermoid cyst: A case report and review of the literature.Surgical neurology international · 2022Article
- Surgery and dose-escalated radiotherapy for aClinical and translational radiation oncology · 2021Article
- Primary Squamous Cell Carcinomas Arising in Intracranial Epidermoid Cysts: A Series of Nine Cases and Systematic Review.Frontiers in oncology · 2021Article
- Hemorrhagic Epidermoid Cyst in Cerebellar Vermis: Case Report and Review of the Literature.Journal of neurological surgery reports · 2021Article
- Primary Intracranial Squamous Cell Carcinoma with a Fatal Course.Asian journal of neurosurgeryArticle
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Authors and funding
6 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Intracranial epidermoid cysts are benign lesions that typically remain asymptomatic; however, although histopathologically benign, these cysts can rarely undergo malignant transformation into squamous cell carcinoma. Primary intracranial squamous cell carcinoma carries a poor prognosis as optimal treatment modalities remain unclear due to their low incidence. Here, we present a case of a cerebellopontine angle epidermoid cyst remnant that underwent malignant transformation into squamous cell carcinoma 40 years after partial resection. To our knowledge, this case establishes the longest time interval to date for an intracranial epidermoid cyst to undergo malignant transformation. We also review the relevant literature and discuss recent retrospective clinical studies that have analyzed the effect of multimodal treatment approaches on survival outcomes in patients with these lesions.
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