ArticleFuture science OA2019
Leveraging phytochemicals: the plant phylogeny predicts sources of novel antibacterial compounds.
Article in Future science OA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The trial behind it
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Who cites it
15 citing papers in PubMed.
- Chemical profile of essential oil from Pimenta racemosa leaves, antioxidant potential, and its enzyme inhibitory properties.Scientific reports · 2025Article
- TLC-bioautography-guided identification and assessment of the antibacterial compounds from Feijoa sellowiana.Phytochemical analysis : PCA · 2025Article
- Bioactive lipids and allelopathic potential of the invasive plantFrontiers in pharmacology · 2025Article
- Integration of In Vitro and In Silico Results From Chemical and Biological Assays ofFood science & nutrition · 2025Article
- Therapeutic Potential of Prenylated Flavonoids of the Fabaceae Family in Medicinal Chemistry: An Updated Review.International journal of molecular sciences · 2024Review
- Exploring Lead-Like Molecules of Traditional Chinese Medicine for Treatment Quest againstBioMed research international · 2024Article
- Leveraging off higher plant phylogenetic insights for antiplasmodial drug discovery.Natural products and bioprospecting · 2023Article
- Ethnopharmacology, Antimicrobial Potency, and Phytochemistry of AfricanAntibiotics (Basel, Switzerland) · 2023Review
- Antibacterial Activity of the Essential Oil FromFrontiers in microbiology · 2022Article
- A Water-Soluble Antibiotic in Rhubarb Stalk Shows an Unusual Pattern of Multiple Zones of Inhibition and Preferentially Kills Slow-Growing Bacteria.Antibiotics (Basel, Switzerland) · 2021Article
- Mimosa tenuiflora's antimicrobial activity on bacteria and fungi from medical importance: an integrative review.Archives of microbiology · 2021Review
- In silico molecular docking and in vitro antimicrobial efficacy of phytochemicals against multi-drug-resistant enteroaggregative Escherichia coli and non-typhoidal Salmonella spp.Gut pathogens · 2021Article
- Reversal of Tetracycline Resistance by Cepharanthine, Cinchonidine, Ellagic Acid and Propyl Gallate in a Multi-drug Resistant Escherichia coli.Natural products and bioprospecting · 2021Article
- Article
- Revealing the secret life of skin - with the microbiome you never walk alone.International journal of cosmetic science · 2020Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe goal of this study was to use phylogenetic evidence to determine plant families with high representation of antibacterial activity and identify potential sources to focus on for antibacterial drug discovery. MATERIALS &
methodsWe reconstructed the molecular phylogeny of plant taxa with antibacterial activity and mapped antibacterial mechanisms of action on the phylogeny.
resultsThe phylogeny highlighted seven plant families (Combretaceae, Cupressaceae, Fabaceae, Lamiaceae, Lauraceae, Myrtaceae and Zingiberaceae) with disproportionately represented antibacterial activity. Phytochemicals produced were primarily involved in the disruption of the bacterial cell wall/membrane and inhibition of quorum sensing/biofilm production.
conclusionThe study provides phylogenetic evidence of seven plant families that should be examined as promising leads for novel antibacterial development.
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Registered trials
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