Evidence map›Paper›PMID 31428415›Full record

ArticleUnited European gastroenterology journal2019

Cost-of-illness of inflammatory bowel disease patients treated with anti-tumour necrosis factor: A French large single-centre experience.

Jean Lawton, Hamza Achit, Lieven Pouillon, Emmanuelle Boschetti, Béatrice Demore, Thierry Matton, Charlène Tournier, Martin Prodel, Laurent Peyrin-Biroulet, Francis Guillemin

Abstract read
In one paragraph

Article in United European gastroenterology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jean LawtonDepartment of Hepato-Gastroenterology, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Hamza AchitCIC 1433 Clinical Epidemiology, Nancy University Hospital, Université de Lorraine, Nancy, France.
Lieven PouillonDepartment of Hepato-Gastroenterology, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.ORCID 0000-0002-3279-1033
Emmanuelle BoschettiDepartment of Pharmacy, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Béatrice DemoreDepartment of Pharmacy, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Thierry MattonDepartment of Medical Information, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Charlène TournierHEVA, Health Economics and Outcomes Research, Lyon, France.
Martin ProdelHEVA, Health Economics and Outcomes Research, Lyon, France.
Laurent Peyrin-BirouletDepartment of Hepato-Gastroenterology, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Francis GuilleminCIC 1433 Clinical Epidemiology, Nancy University Hospital, Université de Lorraine, Nancy, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: No study has evaluated the direct annual costs of inflammatory bowel disease patients treated with anti-tumour necrosis factor therapy. Objectives: The purpose of this study was to identify annual direct costs and main cost drivers of anti-tumour necrosis factor-treated inflammatory bowel disease patients. Methods: All inflammatory bowel disease patients treated with infliximab or adalimumab at Nancy University Hospital were consecutively screened for inclusion from November 2016-February 2017. Data about hospitalisation, surgery, medication, outpatient visits, investigations and transport over the previous 12 months were retrospectively collected. Results: A total of 108 patients ( Conclusions: In a French tertiary referral centre, direct costs of anti-tumour necrosis factor therapy-treated patients were mainly driven by medication, while hospitalisation and surgery represented only a minor part of the costs. There was no difference between Crohn's disease and ulcerative colitis patients.

Indexed as

Cost of IllnessDirect Service CostsAdalimumabAdultAmbulatory CareFemaleFranceGastrointestinal AgentsHospitalizationHumansInflammatory Bowel DiseasesInfliximabMaleTertiary Care CentersTumor Necrosis Factor-alphaAdalimumabGastrointestinal AgentsInfliximabTumor Necrosis Factor-alphaAnti-tumour necrosis factor therapycostsCrohn’s diseaseinflammatory bowel diseasepharmacoeconomicsulcerative colitis

Identifiers

PMID31428415
PMCPMC6683635

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.