ArticleFood science & nutrition2019
Structural characterization and hypolipidemic activities of purified stigma maydis polysaccharides.
Article in Food science & nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 39 citations in OpenAlex.
- Recent Advances in Polysaccharides fromMolecules (Basel, Switzerland) · 2026Review
- Mechanisms and structure-activity relationship of hypolipidemic effects of polysaccharides from natural resources: a review.Archives of pharmacal research · 2026Review
- Research on the Mechanism and Material Basis of Corn (Pharmaceuticals (Basel, Switzerland) · 2024Review
- The regulatory effects of bioactive polysaccharides on intestinal function and bile acids: chemical structures, bioactivities, and mechanisms.Frontiers in nutrition · 2024Review
- Immunomodulatory Activity of Polysaccharides Isolated fromMolecules (Basel, Switzerland) · 2023Article
- Effects of Different Amounts of Corn Silk Polysaccharide on the Structure and Function of Peanut Protein Isolate Glycosylation Products.Foods (Basel, Switzerland) · 2022Article
- Nutritional and Chemical Composition ofFoods (Basel, Switzerland) · 2022Article
- Structural characterization of a novel polysaccharide from sweet corncob that inhibits glycosylase in STZ-induced diabetic rats : Structural characterization of a novel polysaccharide.Glycoconjugate journal · 2022Article
- Improved Oral Bioavailability and Hypolipidemic Effect of Syringic Acid via a Self-microemulsifying Drug Delivery System.AAPS PharmSciTech · 2021Article
- Structural characterization and hypolipidemic activities of purified stigma maydis polysaccharides.Food science & nutrition · 2019Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to investigate structural features and antihyperlipidemic effects of the stigma maydis polysaccharide, termed SMP-1. This polysaccharide was composed of D-mannose, L-rhamnose, D-glucose, D-galactose, L-arabinose, D-xylose, and D-galacturonic acid, with a molar ratio of 1.00:0.21:1.41:1.44:0.70:0.44:0.56. The SMP-1 was mainly bonded by (1 → 6) and (1 → 3) linkages, with various monosaccharides being evenly distributed in the main and side chains. Moreover, SMP-1 had neither triple-helical structure nor molecular aggregation. Importantly, the SMP-1 could effectively bind the bile acids in vitro and significantly lower the total cholesterol, triglyceride, low-density lipoprotein cholesterol levels, and moderately increase the high-density lipoprotein cholesterol level in poloxamer 407-induced hyperlipidemic mice. Moreover, pretreatment with SMP-1 (≥300 mg/kg) could remarkably reduce fat accumulation and restore hepatocyte morphology in the liver of hyperlipidemic mice. Altogether, these findings indicated that SMP-1 could be developed as a safe and effective food supplement for preventing and treating hyperlipidemic disorders.
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