Evidence map›Paper›PMID 31428226›Full record

ArticleOxidative medicine and cellular longevity2019

Antiproliferative and Antitumour Effect of Nongenotoxic Silver Nanoparticles on Melanoma Models.

Lucía M Valenzuela-Salas, Nayeli G Girón-Vázquez, Juan C García-Ramos, Olivia Torres-Bugarín, Claudia Gómez, Alexey Pestryakov, Luis J Villarreal-Gómez, Yanis Toledano-Magaña, Nina Bogdanchikova

Abstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Investigating silver nanoparticles and resiquimod as a local melanoma treatment.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Cancer Therapy by Silver Nanoparticles: Fiction or Reality?International journal of molecular sciences · 2022
    Review
  13. Review
  14. Treatment with ArgovitNanomaterials (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lucía M Valenzuela-SalasEscuela de Ciencias de la Salud, Universidad Autónoma de Baja California, Tijuana, Baja California, Mexico.
Nayeli G Girón-VázquezFacultad de Ingeniería, Arquitectura y Diseño, Universidad Autónoma de Baja California, Ensenada, Baja California, Mexico.
Juan C García-RamosDepartamento de Fisicoquímica de Nanomateriales, CONACyT-UNAM-CNyN, Ensenada, Baja California, Mexico.
Olivia Torres-BugarínPrograma Internacional de Medicina, Universidad Autónoma de Guadalajara, Zapopan, Jalisco, Mexico.
Claudia GómezFacultad de Ingeniería, Arquitectura y Diseño, Universidad Autónoma de Baja California, Ensenada, Baja California, Mexico.
Alexey PestryakovDepartment of Technology of Organic Substances and Polymer Materials, Tomsk Polytechnic University, Tomsk, Russia.
Luis J Villarreal-GómezEscuela de Ciencias de la Ingeniería y Tecnología, Universidad Autónoma de Baja California, Tijuana, Baja California, Mexico.ORCID https://orcid.org/0000-0002-4666-1408
Yanis Toledano-MagañaDepartamento de Fisicoquímica de Nanomateriales, CONACyT-UNAM-CNyN, Ensenada, Baja California, Mexico.ORCID https://orcid.org/0000-0002-2595-7939
Nina BogdanchikovaDepartamento de Fisicoquímica de Nanomateriales, Centro de Nanociencias y Nanotecnología, Universidad Nacional Autónoma de México, Ensenada, Baja California, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last 3 decades, there has been a slow advance to obtain new treatments for malignant melanoma that improve patient survival. In this work, we present a systematic study focused on the antiproliferative and antitumour effect of AgNPs. These nanoparticles are fully characterized, are coated with polyvinylpyrrolidone (PVP), and have an average size of 35 ± 15 nm and a metallic silver content of 1.2% wt. Main changes on cell viability, induction of apoptosis and necrosis, and ROS generation were found on B16-F10 cells after six hours of exposure to AgNPs (IC

Indexed as

AnimalsApoptosisCell Line, TumorCell ProliferationCisplatinDNA DamageErythrocytesKaplan-Meier EstimateMaleMelanoma, ExperimentalMetal NanoparticlesMiceMice, Inbred C57BLReactive Oxygen SpeciesSilverCisplatinReactive Oxygen SpeciesSilver

Identifiers

PMID31428226
PMCPMC6683800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.