Evidence map›Paper›PMID 31428197›Full record

ArticleJournal of infection prevention2019

A case of Crimean-Congo haemorrhagic fever imported in Greece: Contact tracing and management of exposed healthcare workers.

Helena C Maltezou, Anna Papa, Sarantoula Ventouri, Charikleia Tseki, Danai Pervanidou, Androula Pavli, Periklis Panagopoulos, Philothei Markatou, Elpida Gavana, Efstratios Maltezos

Abstract read
In one paragraph

Article in Journal of infection prevention, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Two autochthonous cases of Crimean-Congo haemorrhagic fever and the One Health response, Thessaly, Greece, 2025.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Helena C MaltezouDepartment for Interventions in Health-Care Facilities, Hellenic Center for Disease Control and Prevention, Athens, Greece.ORCID https://orcid.org/0000-0003-0264-3547
Anna PapaDepartment of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Sarantoula VentouriDepartment of Infection Control, University Hospital of Alexandroupolis, Alexandroupolis, Greece.
Charikleia TsekiDepartment of Infection Control, General Hospital of Xanthi, Xanthi, Greece.
Danai PervanidouDepartment for Epidemiological Surveillance and Intervention, Hellenic Center for Disease Control and Prevention, Athens, Greece.
Androula PavliDepartment for Interventions in Health-Care Facilities, Hellenic Center for Disease Control and Prevention, Athens, Greece.
Periklis PanagopoulosDepartment of Infection Control, University Hospital of Alexandroupolis, Alexandroupolis, Greece.
Philothei MarkatouDepartment of Internal Medicine, University Hospital of Alexandroupolis, Alexandroupolis, Greece.
Elpida GavanaDepartment of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Efstratios MaltezosDepartment of Infection Control, University Hospital of Alexandroupolis, Alexandroupolis, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNosocomial transmission is a major mode of infection of Crimean-Congo haemorrhagic fever (CCHF). In May 2018, a patient with CCHF was hospitalised in Greece.

objectiveOur aim was to present the management of healthcare workers (HCWs) to the CCHF case.

methodsContact tracing, risk assessment and follow-up of exposed HCWs were performed. Testing (RT-PCR and/or serology) was offered to contacts. Post-exposure prophylaxis (PEP) with ribavirin was considered for high-risk exposures.

resultsNinety-one HCWs were exposed to the case. Sixty-six HCWs were grouped as high-risk exposures. Ribavirin PEP was offered to 29 HCWs; seven agreed to receive prophylaxis. Forty-one HCWs were tested for CCHF infection; none was found positive. Gaps in infection control occurred. DISCUSSION: CCHF should be considered in patients with compatible travel history and clinical and laboratory findings. Early clinical suspicion and laboratory confirmation are imperative for the implementation of appropriate infection control measures. Ribavirin should be considered for high-risk exposures. Infection control capacity for highly pathogenic agents should increase.

Indexed as

contact tracingCrimean-Congo haemorrhagic feverhealthcare workersinfection controlribavirin

Identifiers

PMID31428197
PMCPMC6683607

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.